Autologous platelet-rich plasma in the treatment of refractory wounds in cutaneous leukocytoclastic vasculitis complicated with hypertension (grade 2 moderate risk): A case report

Yi, Zhongmei; Song, Nali; Zhou, Chen; Fan, Yuxia; Liu, Yueling; Zhang, Bin

doi:10.1016/j.transci.2021.103157

Cited by 2 publications

(4 citation statements)

References 12 publications

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“…A case report by Yi et al . discussed a 46-year-old female with non-healing lower extremity ulcers with black eschars secondary to cutaneous leukocytoclastic vasculitis [ 31 ]. Following topical administration of PRP gel, the wounds healed over the course of 1 month, with marked wound size reduction and new tissue formation.…”

Section: Resultsmentioning

confidence: 99%

Current State of Platelet-rich Plasma in the Treatment of Rheumatic Disease: A Retrospective Review of the Literature

Jacobs

Elghawy

Baruqui

et al. 2023

CRR

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Introduction: Rheumatic diseases are a spectrum of autoimmune or inflammatory diseases that cause damage to the musculoskeletal system as well as vital organs, such as the heart, lungs, kidneys, and central nervous system. Method: The study of rheumatic disease has made great progress in the understanding and management of these conditions in the last few decades using disease-modifying antirheumatic drugs and synthesized biological immunomodulating therapies. However, one potential treatment that has not been well investigated in rheumatic disease is platelet-rich plasma (PRP). PRP is proposed to facilitate the healing of injured tendons and ligaments through a variety of mechanisms, including mitogenesis, angiogenesis and macrophage activation via cytokine release, although its exact mechanism is unclear. Result: There has been a great deal of work in determining the exact preparation method and composition of PRP for regenerative purposes in orthopedic surgery, sports medicine, dentistry, cardiac surgery, pediatric surgery, gynecology, urology, plastic surgery, ophthalmology, and dermatology. Despite this, there is a paucity of research on the impact of PRP on rheumatic disease. Conclusion: This study aims to summarize and evaluate the current research concerning the use of PRP in rheumatic disease.

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Section: Resultsmentioning

confidence: 99%

Current State of Platelet-rich Plasma in the Treatment of Rheumatic Disease: A Retrospective Review of the Literature

Jacobs

Elghawy

Baruqui

et al. 2023

CRR

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“…Also, the treatment of cutaneous leukocytoclastic vasculitis is another application of PRP in the form of PRP gel which has been shown to accelerate the wound closure and granulation tissue formation. In general, using PRP can be a safe and cost‐effective method for different wound healings and it can reduce the duration of treatment 49 …”

Section: Wound Treatment Methodsmentioning

confidence: 99%

“…In general, using PRP can be a safe and cost‐effective method for different wound healings and it can reduce the duration of treatment. 49 …”

Section: Wound Treatment Methodsmentioning

confidence: 99%

“…In general, using PRP can be a safe and cost-effective method for different wound healings and it can reduce the duration of treatment. 49 The use of platelet-rich concentrates (PRC) has also been considered in various medical fields in the last two decades due to its regenerative properties. PRF is actually the second generation of PRCs that is prepared simply by centrifugation of blood in tube.…”

Section: Platelet Therapymentioning

confidence: 99%

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Emerging treatment strategies in wound care

Mirhaj

Labbaf

Tavakoli

et al. 2022

International Wound Journal

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Wound healing is a complex process in tissue regeneration through which the body responds to the dissipated cells as a result of any kind of severe injury. Diabetic and non-healing wounds are considered an unmet clinical need. Currently, different strategic approaches are widely used in the treatment of acute and chronic wounds which include, but are not limited to, tissue transplantation, cell therapy and wound dressings, and the use of an instrument. A large number of literatures have been published on this topic; however, the most effective clinical treatment remains a challenge. The wound dressing involves the use of a scaffold, usually using biomaterials for the delivery of medication, autologous stem cells, or growth factors from the blood. Antibacterial and anti-inflammatory drugs are also used to stop the infection as well as accelerate wound healing. With an increase in the ageing population leading to diabetes and associated cutaneous wounds, there is a great need to improve the current treatment strategies. This research critically reviews the current advancement in the therapeutic and clinical approaches for wound healing and tissue regeneration. The results of recent clinical trials suggest that the use of modern dressings and skin substitutes is the easiest, most accessible, and most cost-effective way to treat chronic wounds with advances in materials science such as graphene as 3D scaffold and biomolecules hold significant promise. The annual market value for successful wound treatment exceeds over $50 billion US dollars, and this will encourage industries as well as academics to investigate the application of emerging smart materials for modern dressings and skin substitutes for wound therapy.cells therapy, platelet therapy, skin tissue engineering, wound dressing, wound healing Key Messages• treatment of wound healing is currently considered an unmet clinical need • currently heavily under research are growth factors and cytokines released from platelets and leukocytes that have a significant effect on the cellular functions such as migration, differentiation, and proliferation, so they can regulate the wound healing process

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Autologous platelet-rich plasma in the treatment of refractory wounds in cutaneous leukocytoclastic vasculitis complicated with hypertension (grade 2 moderate risk): A case report

Cited by 2 publications

References 12 publications

Current State of Platelet-rich Plasma in the Treatment of Rheumatic Disease: A Retrospective Review of the Literature

Current State of Platelet-rich Plasma in the Treatment of Rheumatic Disease: A Retrospective Review of the Literature

Emerging treatment strategies in wound care

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