Autologous Osteochondral Grafting (Mosaic Arthroplasty) for Treatment of Subchondral Cystic Lesions in the Equine Stifle and Fetlock Joints

Bodó, Gábor; Hangody, László; Módis, László; Hurtig, Mark

doi:10.1111/j.1532-950x.2004.04096.x

Cited by 80 publications

(79 citation statements)

References 30 publications

(47 reference statements)

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“…Four to five cylindrical osteochondral grafts (6.5 mm in diameter, 35-40 mm long, spaced approximately 5 mm from each other) were harvested under arthroscopic guidance using a conventional arthroscopic approach. The steps of the harvesting procedure and the instruments used were the same as described previously (Bodó et al, 2004). In the 16-year-old horse, all harvested grafts fractured 2-5 mm under the hyaline cap of both limbs, so transplantation was not performed (Fig.…”

Section: Surgical Proceduresmentioning

confidence: 99%

“…The drilled hole was finally dilated with a calibrated conical dilator 30 mm in depth. Grafts were delivered in a press-fit fashion through the drill guide with the help of an adjustable tamp and seated as flush as possible with the surrounding cartilage (Bodó et al, 2004). The location of each donor and recipient area was recorded on diagrams of the joint surface (Fig.…”

Section: Surgical Proceduresmentioning

confidence: 99%

“…After induction of general anaesthesia, the horses were positioned in dorsal recumbency with the donor limb maximally extended and the recipient limb in flexed position (Bodó et al, 2000;Bodó et al, 2004). The cranial aspect of the medial femoral trochlea (MFT) of a randomly selected right or left limb was used as a donor site.…”

Section: Surgical Proceduresmentioning

confidence: 99%

“…Based on clinical experience in over 1000 MP patients, this technique has become a proven useful alternative for the treatment of 1.0-to 4-cm 2 focal chondral and osteochondral lesions in competitive human athletes (Hangody et al, 2008;Hangody et al, 2010). Clinical experience in the stifle (Bodó et al, 2000;Bodó et al, 2004) and hock (Janicek et al, 2010) joint of horses showed a favourable clinical outcome in all cases.…”

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confidence: 99%

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Mosaic arthroplasty of the medial femoral condyle in horses — An experimental study

Bodó¹,

Vásárhelyi

Hangody

et al. 2014

Acta Veterinaria Hungarica

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One Arabian and 5 Hungarian half-bred horses were used to study the macroscopic and microscopic survival of autologous osteochondral grafts in the weight-bearing surface of the medial femoral condyle (MFC). Grafts were harvested from the cranial surface of the medial femoral trochlea (MFT) under arthroscopic control. Three of them were transplanted into the weight-bearing surface of the contralateral MFC using an arthrotomy approach. Three months later this transplantation procedure was repeated on the opposite stifle joints in the same animals, but at that time transplantation was performed arthroscopically. Follow-up arthroscopy was carried out 12 months after the first operations, and biopsies were taken from both the recipient and the donor sites for histological examination. During follow-up arthroscopy, the transplanted areas looked congruent and smooth. Microscopically, the characteristics of hyaline cartilage were present in 5 out of the 10 biopsies examined; however, in the other half of biopsies glycosaminoglycan (GAG) loss and change in the architecture of the transplanted cartilage was observed. In a 16-year-old horse, all grafts broke during harvesting, and thus transplantation was not performed. No radiological signs of osteoarthritic changes were detected 9 to 12 months after the operations in the donor and recipient joints. Clinically, no lameness or effusion was present three months after the transplantations.

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Section: Surgical Proceduresmentioning

confidence: 99%

Section: Surgical Proceduresmentioning

confidence: 99%

Section: Surgical Proceduresmentioning

confidence: 99%

mentioning

confidence: 99%

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Mosaic arthroplasty of the medial femoral condyle in horses — An experimental study

Bodó¹,

Vásárhelyi

Hangody

et al. 2014

Acta Veterinaria Hungarica

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“…Equine clinical studies in the stifle (Bodó et al, 2000;Bodó et al, 2004) and hock (Janicek et al, 2010) as well as experimental studies (Bodó et al, 2014) using the MP method have demonstrated favourable outcomes with this method.…”

mentioning

confidence: 99%

Evaluation of biomarkers following autologous osteochondral transplantation in the equine stifle joint — An experimental study

Tuska

Tóth

Vásárhelyi

et al. 2016

Acta Veterinaria Hungarica

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The purpose of this study was to evaluate changes in biomarker and synovial parameters following autologous osteochondral transplantation (AOT) in the equine stifle joint, to test the hypothesis whether synovial parameters would show significant differences at selected time points following the surgery (at days 3, 14, 60 and 180) compared to baseline level (at day 0). Surgical intervention was performed in both stifles of nine horses (n = 18). The joints were randomly assigned to operated and sham-operated groups. Grafts 8.5 mm in diameter were harvested from the femoropatellar (FP) joint under arthroscopic control and the medial femorotibial (MFT) joints had AOT using mosaicplasty (MP) instrumentation, while the sham FP and sham MFT joints underwent arthroscopy and miniarthrotomy without transplantation, respectively. Synovial fluid (SF) parameters were evaluated at days 4, 14, 60 and 180. Data were analysed by two-way repeated-measures analysis of variance (ANOVA), and P < 0.05 was considered significant. During the first 10-14 days after surgery, lameness of degree 2-3/5 [American Association of Equine Practitioners (AAEP) scores] was present, which disappeared after 60 days. Joints with transplantation showed significant increases in synovial white blood cell count (WBC), total protein (TP), substance P, C1,2C and CS846 epitope concentration at day 3 compared to baseline and shamoperated joints (P < 0.05). These parameters returned to the baseline values by two months after surgery and remained within normal levels at 6 months postoperatively.

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Transplantation Immunology

Tallmadge¹

2015

Equine Clinical Immunology

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Autologous Osteochondral Grafting (Mosaic Arthroplasty) for Treatment of Subchondral Cystic Lesions in the Equine Stifle and Fetlock Joints

Abstract: Mosaic arthroplasty should be considered for treatment of subchondral bone cysts of the femoral condyle and distal articular surface of the metacarpus/tarsus in horses that are refractory to non-surgical management.

Cited by 80 publications

References 30 publications

Mosaic arthroplasty of the medial femoral condyle in horses — An experimental study

Mosaic arthroplasty of the medial femoral condyle in horses — An experimental study

Evaluation of biomarkers following autologous osteochondral transplantation in the equine stifle joint — An experimental study

Transplantation Immunology

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