Abstract:Although fat grafts obtained by both methods maintain normal histologic structure, the Coleman technique yields a greater number of viable adipocytes and sustains a more optimal level of cellular function within fat grafts and should be considered superior to conventional liposuction as a preferred method of choice for fat graft harvesting.
“…Although technical approaches of harvesting and grafting have been investigated to optimize the surgical protocol, methods to prepare fat prior to grafting remain controversial. Positive results have been reported with the use of fat processed by decantation, 13,14 washing with normal saline in a syringe or open air through a strainer, 15,16 centrifugation at low or high g-force, 17,18 and towel drying, in which fat is placed on a cotton towel, gauze, or Telfa to drain. 19 Supplementation with insulin, growth factors, human albumin, or plasmarich protein has also been used to improve graft retention.…”
“…Although technical approaches of harvesting and grafting have been investigated to optimize the surgical protocol, methods to prepare fat prior to grafting remain controversial. Positive results have been reported with the use of fat processed by decantation, 13,14 washing with normal saline in a syringe or open air through a strainer, 15,16 centrifugation at low or high g-force, 17,18 and towel drying, in which fat is placed on a cotton towel, gauze, or Telfa to drain. 19 Supplementation with insulin, growth factors, human albumin, or plasmarich protein has also been used to improve graft retention.…”
“…Autologous fat facial transplant is a technique that produces long-lasting results. When the fatty tissue is correctly collected and purified through the centrifugation process, adipocyte viability is improved, compared with a conventional liposuction technique [33], and definitive graft survival can be expected in 60-80% of transplanted grafts.…”
Objectives
Antiretroviral therapy has dramatically improved the survival of HIV‐infected children. Nevertheless, side effects comparable to those found in adults have been encountered, such as facial lipoatrophy, which can have a negative impact on the self‐esteem of otherwise healthy adolescents. Cosmetic surgical procedures in adolescents raise psychological issues which need to be specifically addressed and which have never been previously reported in this population. We evaluated the patient satisfaction, safety and cosmetic results of HIV‐infected adolescents who experienced autologous fat transplants for the correction of facial lipoatrophy.
Methods
We report the results of plastic surgery using autologous fat transplants (Coleman's Lipostructure™) in six HIV‐infected adolescents with facial lipoatrophy: three boys and three girls, aged 14–19 years.
Results
The quantity of reinjected fat on each side of the face varied from 5 to 12 mL within a single procedure. All the patients reported being satisfied or very satisfied with the cosmetic results and reported a positive impact on their daily life.
Conclusions
With well‐trained surgeons and carefully selected indications, corrective surgery of facial lipoatrophy in HIV‐infected adolescents can provide immediate and long‐lasting benefits in terms of physical appearance and psychological wellbeing, and should be considered as a component of comprehensive care.
“…The use of autologous fat grafting has been successfully used in facial, lip and hand rejuvenation, and also for body contour improvement (1). Autologous fat is a favourable filler; however, fat absorption at the grafted site may equal 70% of the filler volume (1).…”
A 61-year-old man developed a squamous cell carcinoma on his left lower lip, which was initially excised with positive margins. He subsequently developed lymphadenopathy within the left neck and was referred to the Division of Otolaryngology -Head and Neck Surgery at the Queen Elizabeth II Health Sciences Centre (Halifax, Nova Scotia). He underwent a second wedge resection of the left lower lip with an ipsilateral functional neck dissection. The patient received postoperative radiotherapy to the lip and neck at a total dose of 66 Gy. As a result of his combined modality treatment, he developed a whistle deformity, marked by lip incontinence and an asymmetric smile, and was referred to another member of the head and neck team who was an expert in facial plastic surgery for potential fat augmentation and reconstruction of his lower lip (Figure 1).It was decided that the patient would receive hyaluronic acid-based injectable tissue filler for temporary augmentation, followed by treatment with autologous microfat transplantation to the lip for definitive augmentation. Following the tissue filler injection, it was noted that the patient had closure of the lateral lip margin, improvement in lip competence and a pleasing aesthetic result. However, on reassessment three months later, the patient reported having issues of lip incompetence, once again, due to the relatively premature degradation of the tissue filler and subsequent reformation of his whistle deformity.A decision was then made to proceed with autologous microfat transplantation to the lip. The donor site chosen by the senior author was the abdomen, and a series of three injections was A whistle deformity is defined as a deficiency in the vertical length of the lip so that the free margins of the upper and lower lips do not meet normally, giving the appearance of whistling. This is a common secondary deformity of the vermilion in patients with cleft lip. A case involving a 61-year-old man who developed a whistle deformity as a result of two wedge resections and postoperative radiotherapy for treatment of squamous cell carcinoma of the lower lip is presented. Hyaluronic acid-based tissue filler and autologous microfat transplantation to the lower lip were used for definitive management of the patient's whistle deformity. After one year of follow-up, the patient was pleased with the overall result and noted marked improvement of his oral competence and overall appearance of the lip. The present case demonstrates that microfat transplantation is a viable option for correcting a whistle deformity, not only after surgery, but also following adjuvant radiotherapy -both of which potentially reduce graft viability secondary to decreased vascularity of the recipient site.
Key Words: Autologous fat grafting; Postoperative radiotherapy; Whistle deformityUn cas de microgreffe de graisse autologue dans la reconstruction d'une déformation du vermillon de la lèvre après un traitement oncologique La déformation du vermillon se définit comme une anomalie de la partie vertica...
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