Autologous Fat Grafting With Combined Three-Dimensional and Mirror-Image Analyses for Progressive Hemifacial Atrophy

Yang, Xiaonan; Wu, Rongwei; Bu, Hui; Lu, Hongxiang; Jia, Zhenhua; Jin, Xiaolei; Qi, Zuoliang

doi:10.1097/sap.0000000000000641

Cited by 16 publications

(15 citation statements)

References 24 publications

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“…The majority of patients with HIV-associated lipodystrophy (n = 500 of 650 [76.9%]) were men, and the mean age at the time of the first AFT session was 42.6 years (95% CI, 34.4-46.7). Furthermore, 16 studies 10, [14][15][16]25,26,28,32,43,47,50,52,53,[57][58][59] consisting of 409 patients evaluated AFT in patients with congenital disorders. From this group, 201 (49.1%) patients suffered from Parry-Romberg syndrome, 181 (44.3%) from craniofacial microsomia, and the remaining 27 patients (6.6%) represent a mixed group of craniofacial microsomia, Goldenhar syndrome, and Treacher Collins from a single study.…”

Section: Populationmentioning

confidence: 99%

“…From 16 studies addressing fat resorption through volume measurements, 3 attempted to estimate volume changes by evaluating tissue thickness using ultrasonography or computed tomography (CT) scan and were excluded from the analysis. 8,16,48 The remaining 13 studies used appropriate imaging techniques, such as 3-dimensional image capture devices 25,28,36,50,53,58 or CT. 14,19,20,43,52 Eight of these investigated volume retention in exclusively congenital patients (Parry-Romberg and craniofacial microsomia), while the remaining 5 involved patients with HIV-associated lipodystrophy. The percentage graft retention represents the fraction of the measured gain in volume, relative to the total volume of injected fat.…”

Section: Volume Measurementsmentioning

confidence: 99%

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Efficacy and Safety of Autologous Fat Transfer in Facial Reconstructive Surgery

Krastev

Beugels

Hommes

et al. 2018

JAMA Facial Plast Surg

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IMPORTANCEThe use of autologous fat transfer (AFT) or lipofilling for correcting contour deformities is seen as one of the major breakthroughs in reconstructive plastic surgery. Its applications in facial reconstructive surgery have been of particular interest owing to the prospect of achieving autologous reconstruction by a minimally invasive approach. However, its unpredictability and variable degree of resorption have limited its utility and much skepticism still exists regarding its efficacy. Furthermore, more than 2 decades of clinical research have produced a highly fragmented body of evidence that has not been able to provide definite answers. OBJECTIVE To investigate the safety and efficacy of AFT in facial reconstruction through a systematic review and meta-analysis.

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Section: Populationmentioning

confidence: 99%

Section: Volume Measurementsmentioning

confidence: 99%

Efficacy and Safety of Autologous Fat Transfer in Facial Reconstructive Surgery

Krastev

Beugels

Hommes

et al. 2018

JAMA Facial Plast Surg

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“… 1 , 2 It is available in easily accessible subcutaneous depots but also can be molded to reconstruct defects, especially in terms of patients with mild to moderate forms. 3 Traditional fat transplantation often has unreliable long-term results because of absorption and volume loss. 4 As a result, several different techniques of lipofilling have been developed in recent years.…”

mentioning

confidence: 99%

“…Autologous fat grafting has been 1 of the most frequently and effectively performed procedures for obtaining the desired symmetrical facial appearance 1,2 . It is available in easily accessible subcutaneous depots but also can be molded to reconstruct defects, especially in terms of patients with mild to moderate forms 3 . Traditional fat transplantation often has unreliable long-term results because of absorption and volume loss 4 .…”

mentioning

confidence: 99%

High-Density Fat Grafting Assisted Stromal Vascular Fraction Gel in Facial Deformities

Cao

Wang

et al. 2021

Journal of Craniofacial Surgery

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Autologous fat grafting is commonly used for soft tissue augmentation and reconstruction, this technique is limited by a high rate of graft absorption. The stromal vascular fraction gel (SVF-gel) grafting for facial volume augmentation can exert a positive effect on skin rejuvenation, but its major limitation is the low rate of conversion of Coleman fat. The purpose of our study was to investigate a novel surgery using performing high-density fat in combination with SVF-gel in the treatment of hemifacial atrophy, or Romberg diseases. From October 2017 to October 2019, 13 patients with hemifacial atrophy underwent high-density fat transfer with SVF-gel injection. The outcome was determined by the difference in presurgery and postsurgery FACE-Q modules (FACE-Q conceptual framework: 1, Satisfaction with Facial Appearance; 2, Health-Related Quality of Life; 3, Negative Sequelae; 4, Satisfaction with Process of Care), which were designed as patient-reported outcome instrument to evaluate the unique outcomes of patients undergoing facial cosmetic procedures. The excellent cosmetic results were observed during follow-up periods, with no adverse events was seen in the treatment group. All patients showed improvements in facial augmentation and contour. In patients with facial volume loss, high-density fat transfer with SVF-gel facial injection resulted in significantly higher improvement scores and better patient satisfaction. The patient-reported FACE-Q modules presurgery and postsurgery results showed statistically significant improvement ( P < 0.05). This high-density fat in combination with SVF-gel is an effective method of correcting the facial volume loss that leave no complications during follow-up, having a satisfactory volumization effect. This could largely facilitate the clinical utilization of fat.

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“…Its accuracy and validation in evaluation of facial fat grafting has been proved by our group. 22 Moreover, the term percentage volume maintenance has emerged as a promising indicator in evaluating the effect of fat grafting with 3-D technology. 23 However, previous articles about 3-D tech-niques have not gone beyond emphasizing the importance of a certain fat-processing technique.…”

mentioning

confidence: 99%

Three-dimensional Volumetric Analysis of 3 Fat-Processing Techniques for Facial Fat Grafting

Yang

Jin

et al. 2018

JAMA Facial Plast Surg

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IMPORTANCE Autologous fat grafting has revolutionized the field of facial soft-tissue augmentation, despite a lack of standardization. Objective data are needed to arrive at consensus regarding the best technique for optimal volume retention. OBJECTIVE To compare 3 fat-processing techniques with 3-dimensional (3-D) technology to explore the optimal fat-processing technique for improving the volume retention of grafted fat.

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Autologous Fat Grafting With Combined Three-Dimensional and Mirror-Image Analyses for Progressive Hemifacial Atrophy

Abstract: The facial symmetry of patients with centered FMP can be successfully restored using serial AFG alone. The combined 3D and MIA can be used to predict the volumetric deficiency of soft tissues and objectively evaluate the survival of grafted fat.

Cited by 16 publications

References 24 publications

Efficacy and Safety of Autologous Fat Transfer in Facial Reconstructive Surgery

Efficacy and Safety of Autologous Fat Transfer in Facial Reconstructive Surgery

High-Density Fat Grafting Assisted Stromal Vascular Fraction Gel in Facial Deformities

Three-dimensional Volumetric Analysis of 3 Fat-Processing Techniques for Facial Fat Grafting

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