Abstract:Autoinflammatory Diseases (AIDs) are a vast spectrum of disorders characterized by recurrent attacks of sterile inflammation. Since the first cloning of the Familial Mediterranean Fever gene in 1997, there has been a rapid rate of discovery of new AIDs. As of 2022, there have been 485 inborn errors of immunity documented by the International Union of Immunological Societies, for which many display aspects of autoinflammation. The pathophysiology of AIDs is complex. While many are caused by rare mutations in ge… Show more
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