Autoimmune Progesterone Dermatitis of Pregnancy

Bierman, Stanley M.

doi:10.1001/archderm.1973.01620210060016

Cited by 69 publications

(25 citation statements)

References 27 publications

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“…Skin lesions include urticaria, angioedema, erythema multiforme, eczema, folliculitis, papulovesicular eruptions, fixed drug eruption, purpura, or vulvovaginal pruritus (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). Anaphylaxis is also reported (21)(22)(23).…”

Section: In Vitro Fertilizationmentioning

confidence: 99%

Autoimmune progesterone dermatitis: clinical presentation and management with progesterone desensitization for successful in vitro fertilization

Prieto-García¹,

Sloane²,

Gargiulo³

et al. 2011

Fertility and Sterility

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Section: In Vitro Fertilizationmentioning

confidence: 99%

Autoimmune progesterone dermatitis: clinical presentation and management with progesterone desensitization for successful in vitro fertilization

Prieto-García¹,

Sloane²,

Gargiulo³

et al. 2011

Fertility and Sterility

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“…In addition, intracutaneous endocrine skin tests using progesterone and oestradiol revealed no abnormal immediate or delayed responses, thereby excluding an autoimmune response to progesterone, as previously described. 72 Faber et al 71 concluded that their patients had the same disorder as described by Bourne 69 as toxaemic rash of pregnancy. They felt that the possibility that this condition was an early form of PG was worthy of further investigation.…”

Section: Prurigo Of Pregnancymentioning

confidence: 78%

Skin disorders in pregnancy

Jones

Black²

1997

Fet. Matern. Med. Rev.

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During pregnancy there are profound metabolic, endocrine and vascular changes which are tolerated for a short period of time. As the skin represents the largest organ of the body, these changes are also reflected in the appearance of the skin both by the improvement or exacerbation of pre-existing skin disease and by the development of new dermatoses. The specific dermatoses of pregnancy are a group of disorders which only occur in the pregnant state.This review will discuss the physiological effects of pregnancy on the appearance and function of normal skin, and other cutaneous diseases affected by pregnancy (including intrahepatic cholestasis). The latter part of the review will discuss important aspects of the specific dermatoses of pregnancy.

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“…In addition, APD during pregnancy has been associated with spontaneous abortions [2,25]. Pregnancy is associated with an increase of maternal progesterone levels, which may explain the initiation or worsening of symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…In regards to an improvement of symptoms during pregnancy, a number of theories have emerged. Explanations include a slow rise of progesterone during pregnancy that acts as a method of desensitization, a decrease in maternal immune response during pregnancy, or an increased production of anti-inflammatory glucocorticoids [13,25,26]. …”

Section: Discussionmentioning

confidence: 99%

Autoimmune progesterone dermatitis in a patient with endometriosis: case report and review of the literature

Baptist

Baldwin

2004

Clin Mol Allergy

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Autoimmune progesterone dermatitis (APD) is a condition in which the menstrual cycle is associated with a number of skin findings such as urticaria, eczema, angioedema, and others. In affected women, it occurs 3–10 days prior to the onset of menstrual flow, and resolves 2 days into menses. Women with irregular menses may not have this clear correlation, and therefore may be missed. We present a case of APD in a woman with irregular menses and urticaria/angioedema for over 20 years, who had not been diagnosed or correctly treated due to the variable timing of skin manifestations and menses. In addition, we review the medical literature in regards to clinical features, pathogenesis, diagnosis, and treatment options.

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Autoimmune Progesterone Dermatitis of Pregnancy

Cited by 69 publications

References 27 publications

Autoimmune progesterone dermatitis: clinical presentation and management with progesterone desensitization for successful in vitro fertilization

Autoimmune progesterone dermatitis: clinical presentation and management with progesterone desensitization for successful in vitro fertilization

Skin disorders in pregnancy

Autoimmune progesterone dermatitis in a patient with endometriosis: case report and review of the literature

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