Autoimmune hemolytic anemia associated with mesenteric teratoma

Abstract

The paper describes a case of autoimmune hemolytic anemia (AIHA) in a 27-year-old woman whose examination revealed mesenteric teratoma. AIHA was characterized by a hypertensive crisis and a temporary response to corticosteroid therapy that was complicated by the development of somatogenic psychosis and discontinued. A relapse of hemolysis developed 6 months later. The patient underwent laparoscopic splenectomy and removal of mesenteric root teratoma. Immediately after surgery, a hematological response was obtained as relief of hemolysis and restoration of a normal hemoglobin level. There is a sustained remission of AIHA for the next 16 months.

Autoimmune hemolytic anemia due to mediastinal teratoma: A case report and review article

“…Also there have been a few articles in which an association between AIHA and ovarian teratoma has been reported. In another case report, AIHA was accompanied by a mesenteric teratoma 10 . But we could not find any case reports demonstrating mediastinal teratoma as the underlying cause of AIHA, so this article seems to be the first case report regarding this issue.…”

“…In another case report, AIHA was accompanied by a mesenteric teratoma. 10 But we could not find any case reports demonstrating mediastinal teratoma as the underlying cause of AIHA, so this article seems to be the first case report regarding this issue. Teratomas are frequently localized in sacrococcygeal and gonadal regions, though, they can be localized in other areas such as the neck, mediastinum, retroperitoneum, nasopharynx, and maxillary regions.…”

Anemia and diseases of the gastrointestinal tract

“…Заболевания пищеварительной системы способствуют нарушению всасывания указанных экзогенных гемопоэтинов, и/или их потери (при ЖДА), и/или блокаде их реутилизации [10]. Реже отмечается первичная гипоплазия костного мозга (при вирусных гепатитах) [11,12] и разрушение эритроцитов и/или эритрокариоцитов при аутоиммунных либо паранеопластических процессах (аутоиммунная гемолитическая анемия при целиакии, карциноиде желудка, патологии тонкой кишки) [13,14].…”