Autoimmune Diseases of the Innate and Adaptive Immune System including Atopic Dermatitis, Psoriasis, Chronic Arthritis, Lyme Disease, and Alzheimers Disease

Precision Medicine: The Role of the MSIDS Model in Defining, Diagnosing, and Treating Chronic Lyme Disease/Post Treatment Lyme Disease Syndrome and Other Chronic Illness: Part 2

“…It is important to identify potential multifactorial causes of chronic diseases, since health care costs are rising, with a recent health care survey reporting that almost half of all Americans suffer from at least one of 10 chronic conditions [159]. Autoimmunity can result from antibodies produced against Borrelia that cross react with our own tissue antigens (molecular mimicry), while bacteria activate Toll-like receptor 2 (TLR-2), [160,161] furthering increases in the pro-inflammatory cytokines, TNF-alpha and IL-17. Similarly, mercury (Hg), bisphenol A (BPA), asbestos, and small particle pollution have now been published in the medical literature as potential factors increasing autoimmune reactions [37,51,101,102].…”

Alzheimer’s Disease: Assessing the Role of Spirochetes, Biofilms, the Immune System, and Amyloid-β with Regard to Potential Treatment and Prevention

“…Where spirochetes have been found in the brains of Alzheimer’s disease (AD), it may be considered an infectious disease; this is the first and most important consideration [ 1, 2 ]. It is also a chronic disease, a biofilm-associated disease, [ 3 ] and an autoimmune disease [ 4 ]. Further, it is a debilitating disease, a socially-destructive disease, an exceedingly expensive disease, and, lastly, a deadly disease [ 5 ].…”

“…These stimuli include salt and water, as seen in eczema and tinea versicolor [ 10, 11 ]. Low dose antibiotics and quorum sensing are seen in psoriasis [ 12 ] and arthritis [ 4 ]. Further, elevated temperatures and exposure to alcohol and other chemicals promote biofilms [ 13 ].…”

Awareness of Lyme Borreliosis of the Patients of Ternopil Regional Tb Dispensary

“…However, sarcoidosis can be caused by other etiological factors: infections (viruses: herpes, Epstein-Barr, retrovirus, coxsackie B virus, cytomegalovirus, bacteria: Propionibacterium acnes, Mycobacterium tuberculosis and other mycobacteria, Mycoplasma), inorganic (beryllium, zirconium and aluminum) and organic (pollen, clay) agents [2,4,7,10,16]. Lyme disease has many symptoms similar to those in sarcoidosis and tuberculosis (lesions of pleura, heart, joints, nervous system, skin) [6,8,9,18]. Assumptions about of borreliosis and sarcoidosis connection are based on the geographical spread of both diseases and family manifestations of these diseases [2,4,13].…”