Autogenous DDM versus Bio‐Oss granules in GBR for immediate implantation in periodontal postextraction sites: A prospective clinical study

Li, Peng; Zhu, HuiCong; Huang, Dahong

doi:10.1111/cid.12667

Cited by 59 publications

(89 citation statements)

References 22 publications

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“…Out of the 23 studies (Table 1), there were 11 randomised controlled clinical trials [21-24, 26, 29-32, 36, 37, 39], one prospective cohort study [34,40], three retrospective cohort studies [18,20,33], and eight case series [16,17,19,25,27,28,35,38,[41][42][43], of which two research groups independently published two follow-up papers on the same study cohort [21,22,27,28], and they have been collectively grouped under one study name for this analysis. The follow-up period after ridge augmentation or implant placement was reported in all studies except two [16,35], and it ranged from 3.1 months to 10 years.…”

Section: Study Design and Characteristicsmentioning

confidence: 99%

Clinical and histological sequelae of surgical complications in horizontal guided bone regeneration: a systematic review and proposal for management

Tay

Lu²,

Lai

et al. 2020

Int J Implant Dent

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It is not uncommon to encounter post-surgical complications after horizontal guided bone regeneration (GBR). The primary aim of this review was to evaluate the incidence and types of complications that occur after horizontal GBR and propose management strategies to deal with these clinical situations. A secondary aim was to conduct a histomorphometric review of the wound healing process at sites that experienced post-surgical complications after GBR. A keyword search of MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials for studies published in English from January 2015 to January 2020 was conducted for the primary aim and 23 studies were selected. A second search addressing the secondary aim was conducted, and five studies were included. Site-level analysis showed that the weighted mean incidence proportion of minor wound dehiscence and minor infections occurring at the augmented site was 9.9% [95% CI 6.4, 13.9, P < 0.01] and 1.5% [95% CI 0.4, 3.1, P = 0.21) respectively. Patient-level analysis showed minor and major complications occurring at a weighted mean incidence proportion of 16.1% [95% CI 11.9, 20.8, P = 0.01] and 1.6% [95% CI 0.0, 4.7, P < 0.01] respectively, while neurosensory alterations at the donor site was 7.0% [95% CI 1.3, 15.5, P < 0.01]. Subgroup analysis also revealed that the use of block grafts increased the incidence proportion of minor post-surgical complications, whereas a staged GBR procedure increased the incidence proportion of both minor and major post-surgical complications. Although exposure of the barrier membrane is often associated with less bone regeneration and graft resorption, the type of membrane used (resorbable or non-resorbable) had no statistically significant influence on any post-surgical complication. Histologically, a layer of fibrous connective tissue instead of bone is commonly observed at the interface between the native bone at the recipient site and the regenerated bone in cases with membrane exposure after GBR procedure. Minor wound dehiscence was the highest incidence proportion of post-surgical complications. Methods ranging from daily application of antiseptics, use of systemic antimicrobials, regular reviews, and total removal of the non-integrated biomaterials are commonly prescribed to manage these post-surgical complications in attempt to minimise the loss of tissue at the surgical site.

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Section: Study Design and Characteristicsmentioning

confidence: 99%

Clinical and histological sequelae of surgical complications in horizontal guided bone regeneration: a systematic review and proposal for management

Tay

Lu²,

Lai

et al. 2020

Int J Implant Dent

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“…The main procedures reported by the few randomised controlled trials in literature are resumed in Table 2, using dentine derivates as socket preservation, guided bone regeneration and sinus augmentation [41,[43][44][45][46][47] Demineralised dentin vs. mineralised dentin Alveolar preservation…”

Section: Osteo-genesismentioning

confidence: 99%

Autologous Materials in Regenerative Dentistry: Harvested Bone, Platelet Concentrates and Dentin Derivates

2020

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The jawbone is a peculiar type of bone tissue, unique for its histological, anatomical and physiological characteristics. Therefore, a defect in the maxilla or in the mandible, because of pathological sequelae is difficult to prevent and to restore. Several biomaterials have been and are currently being developed to respond to the demands of regenerative medicine. A specific group of biomaterials used in regenerative dentistry is represented by the autologous materials. Platelet concentrates harvested bone and dentin derivates are indeed used in an attempt to minimise the alveolar resorption or in vertical ridge augmentation procedures or in sinus lift interventions. The aim of this review is to examine the properties of the above-listed materials, to compare them and to indicate eventual clinical applications.

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“…A report of a previous case of long-term follow-up (5 years) reported 1 mm of buccal marginal bone resorption around the implant with the formation of cortico-cancellous bone, approximately six years after socket preservation in 2016 [9]. So far, Auto-DDM accelerates bone regeneration in numerous human clinical studies [10,11]. Recently, a fragmented, partially demineralized tooth matrix was used for maxillary sinus augmentation.…”

Section: Introductionmentioning

confidence: 99%

Allogeneic Demineralized Dentin Matrix Graft for Guided Bone Regeneration in Dental Implants

Kim

et al. 2020

Applied Sciences

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Autogenous and allogeneic demineralized dentin matrices (Auto-DDM and Allo-DDM, respectively) are currently used for guided bone regeneration (GBR). Buccal marginal bone (BMB) resorption is critical for successful implant integration. This study analyzed BMB resorption around dental implants for GBR between the control group (Auto-DDM graft) and experimental group (Allo-DDM graft). From 2014 to 2019, we enrolled 96 patients (59 males, 37 females, average 57.13 years) who received GBR (52 and 44 using Allo-DDM and Auto-DDM, respectively,) without a barrier membrane and a simultaneous single dental implantation (54 in the maxilla and 42 in the mandible). BMB height was measured immediately after GBR, at prosthetic loading, and 12 months after loading. BMB resorption was classified as initial resorption (between GBR and prosthetic loading) and functional resorption (during 12 months after prosthetic loading). The differences in the BMB levels of Auto-DDM and Allo-DDM were analyzed between the initial and functional resorption stages by independent sample t-test. Auto-DDM and Allo-DDM showed similar BMB changes in initial resorption (0.73 ± 0.97 and 0.72 ± 0.77 mm, respectively) and functional resorption (0.69 ± 0.81 and 0.48 ± 0.58 mm, respectively) without a significant difference between the maxilla and mandible. For GBR, Allo-DDM is comparable to Auto-DDM in terms of BMB resorption.

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Autogenous DDM versus Bio‐Oss granules in GBR for immediate implantation in periodontal postextraction sites: A prospective clinical study

Abstract: The autogenous DDM granules prepared at the chairside after extractions could act as an excellent readily available alternative to bone graft material in GBR, even for implantation of severe periodontitis cases.

Cited by 59 publications

References 22 publications

Clinical and histological sequelae of surgical complications in horizontal guided bone regeneration: a systematic review and proposal for management

Clinical and histological sequelae of surgical complications in horizontal guided bone regeneration: a systematic review and proposal for management

Autologous Materials in Regenerative Dentistry: Harvested Bone, Platelet Concentrates and Dentin Derivates

Allogeneic Demineralized Dentin Matrix Graft for Guided Bone Regeneration in Dental Implants

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