Investigation of the relationships between information, reality and cognition targets the structuralprocedural properties of organisms as living systems. Nature tends towards hierarchical forms of both structure and process, and consequently any study of information in this context must of necessity take account of the characteristics of existing scales and their interfaces. The situation is complicated by the pragmatic tendency of evolution to scavenge prior existing features in creating new ones, and consequently biology does not uniquely exhibit hierarchical configurations. This paper addresses the nature of hierarchical organization and the origin of information in a biological context; although the ideas presented here can be applied almost equally well to non-biological entities where hierarchy is less-well defined or extant.We have previously published [1, 2] extensive details of the relationships between different scales or levels of organization in living systems, and here we will only refer to those characteristics which are relevant to our present purpose. Dodig-Crnkovic and Giovagnoli [3] have described Nature as a hierarchically-organized network of networks, which corresponds well to our own viewpoint. Multiscalar systems are by their very nature unified, and this unification is a real characteristic of any system [4], which integrates all of the system's scales into a scale-free hyperscalar representation in which simplified replicas of the 'real' scales are 'objectively' (more-than-subjectively) accessible, in the sense that Havel [5] has (socially) defined 'objective' as a 'group subjective'. The transition from