Author Correction: GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome

Single-cell RNA sequencing reveals that the immunosuppression landscape induced by chronic stress promotes colorectal cancer metastasis

“…A reliable study has proven that CD8 + T cells are expanded in colitis patients, which is dynamically related to tissue-resident memory cells (Trms) [ 41 ], which suggests the particularity of the TIME of CRC. A study showed that CD8 + T effector memory cells with high expression of GZMK are associated with worse outcomes in CRC patients [ 42 ]. Interestingly, in our research, the identified T-cell subsets including Activated CD8+T cells, Effector CD8+T cells, Naive CD8+T cells, Terminal exhausted CD8+T cells, all highly expressed GZMK, and among them, Activated CD8+T cells, Naive CD8+T cells, Terminal exhausted CD8+T cells whose proportions increased in CUMS group tumours, also highly express CCR7(a marker of CD8+T central memory cells) ( Fig.…”