Author Correction: Clinical Manifestations and Ophthalmic Outcomes of Ocular Syphilis at a Time of Re-Emergence of the Systemic Infection

Furtado, João M.; Arantes, Tiago Eugênio Faria e; Nascimento, Heloísa; Vasconcelos-Santos, Daniel Vítor; Nogueira, Natália; Queiroz, Rafael de Pinho; Brandão, Luana P.; Bastos, Thaís Marino de Azeredo; Martinelli, Ricardo; Santana, Rodrigo de Carvalho; Muccioli, Cristina; Belfort, Rubens; Smith, Justine R.

doi:10.1038/s41598-018-34170-8

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“…In our study, the most common form of uveitis among patients with ocular syphilis was non-granulomatous anterior uveitis followed by posterior involvement. However, among the 129 patients in the previously mentioned study by Furtado et al [24] found that posterior uveitis accounts for the majority of cases of ocular syphilis most commonly posterior placoid chorioretinitis and syphilitic punctate inner retinitis. Another study from France also found most patients to be mostly posterior placoid chorioretinitis [29] .…”

Section: Resultsmentioning

confidence: 95%

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Ocular syphilis resurgence in an urban underserved community in the United States

Tam¹,

Martín²,

Fridman³

et al. 2022

Int J Ophthalmol

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AIM: To evaluate the clinical characteristics, demographics, and visual outcomes of patients with ocular syphilis at an urban hospital to increase awareness and assist in earlier diagnosis and treatment of the resurgent disease. METHODS: A retrospective chart review was performed on patients with ICD-9 and ICD-10 diagnosis codes correlating with syphilis or syphilis-related ocular diseases between 2010 and 2019. Variables evaluated included age, gender, race, vision, ocular findings, human immunodeficiency virus (HIV) status and men who have sex with men status, recreational drug and alcohol use. RESULTS: Ocular syphilis was diagnosed in 40 patients (53 eyes) of a total of 229 patients who tested positive for syphilis via serum and/or cerebrospinal fluid treponemal testing from 2010-2019. Among patients with ocular syphilis, most patients were males, aged 45 or above and Black, and had no diagnosed HIV infection. Approximately 50% patients had 20/40 vision or better. Nearly 50% had non-granulomatous anterior uveitis as their initial presentation, and 49% of patients had involvement of the posterior segment. Neovascular glaucoma (5.7%), papillitis (7.5%), vasculitis (5.7%), and retinal detachment (5.7%) were rarer presentations of the disease and were associated with a poorer visual prognosis. CONCLUSION: Given the increased prevalence and protean manifestations of syphilis, early diagnosis and treatment are paramount. More studies on ocular syphilis are warranted to understand this resurging disease.

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Section: Resultsmentioning

confidence: 95%

“…In our study, 11/53 (20.75%) had poor visual outcomes with vision less than 20/400, with 7/11 (63.64%) of those with posterior involvement. However, a study by Furtado et al [24] found most patients to have visual acuity of 20/50 or worse, and had posterior involvement.…”

Section: Resultsmentioning

confidence: 97%