Authenticated QKD Based on Orthogonal States

Xiong, Qiaoling; Hou, Fen; Liu, Bin; Huang, Wei; Xu, Bingjie; Li, Yang

doi:10.1007/s10773-022-05140-8

Cited by 1 publication

(2 citation statements)

References 27 publications

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“…[ 7 ] Specifically, it was observed that pancreatic β‐cell destruction could be triggered by UA‐mediated oxidative damage. [ 8 ] Moreover, it was also demonstrated that oxidative stress associated with the accumulation of UA resulted in a reduction of insulin secretion via an effect on the expression of the gene that codes for insulin. [ 8,9 ]…”

Section: Introductionmentioning

confidence: 99%

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Vitamin D Reduces the Activity of Adenosine Deaminase and Oxidative Stress in Patients with Type Two Diabetes Mellitus

Alfaqih,

Ababneh,

Mhedat

et al. 2024

Molecular Nutrition Food Res

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ScopePatients with Type 2 diabetes mellitus (T2DM) have lower levels of vitamin D. An elevation in uric acid (UA) contributes to T2DM via an increase in oxidative stress. Adenosine deaminase (ADA) is an enzyme of the purine degradation pathway. It is hypothesized that a reduction of ADA activity via vitamin D supplementation reduces UA and oxidative stress.Methods and resultsA total of 162 participants (81 with T2DM and 81 controls) are enrolled in a case–control study. A follow‐up interventional study is performed on 30 patients with vitamin D deficiency. These patients receive 50 000 IU (international units) of vitamin D3 on a weekly basis for 12 weeks. This intervention is followed by the measurement of several markers. T2DM patients has higher ADA activity, UA, and lipid peroxidation but lower 25‐hydroxy‐vitamin D (25 (OH) vitamin D) and GSH/GSSG ratio (p < 0.05). Vitamin D supplementation results in a reduction of ADA activity and UA levels (p < 0.05) along with an increase in GSH/GSSG ratio (p < 0.05).ConclusionThe results highlight the presence of an axis in T2DM patients between ADA, UA, and oxidative stress. Modulation of this axis can be achieved by clinically approved vitamin D supplementation protocols.

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Section: Introductionmentioning

confidence: 99%

“…[ 8 ] Moreover, it was also demonstrated that oxidative stress associated with the accumulation of UA resulted in a reduction of insulin secretion via an effect on the expression of the gene that codes for insulin. [ 8,9 ]…”

Section: Introductionmentioning

confidence: 99%