Ausência de efeito antinociceptivo decorrente da administração intravenosa de crotalfina em comparação com morfina, U50-488H ou fenilbutazona em equinos submetidos à estimulação térmica da pele íntegra

Guirro, Erica Cristina Bueno do Prado; Perotta, João Henrique; Paula, Márcio de; Cury, Yara; Valadão, Carlos Augusto Araújo

doi:10.1590/s0103-84782013005000021

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“…Besides pre-clinical studies, there is only one study that had already evaluated antinociception promoted by crotalphine and no analgesia was observed in horses submitted to thermal stimulation on intact skin (GUIRRO et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Clinical, behavioral and antinociceptive effects of crotalphine in horses

Guirro

Perotta

Paula³

et al. 2015

Cienc. Rural

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Section: Introductionmentioning

confidence: 99%

Clinical, behavioral and antinociceptive effects of crotalphine in horses

Guirro

Perotta

Paula³

et al. 2015

Cienc. Rural

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Literature Review on Crotalus durissus terrificus Toxins: From a Perspective of Structural Biology and Therapeutic Applications

Macedo

Lima

Kayano

et al. 2023

CPPS

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Background: The venom of Crotalus durissus terrificus, as well as its fractions, has intrigued research groups worldwide who are working to isolate, characterize, and find possible biotechnological applications. A number of studies have elucidated that these fractions and their derivatives possess pharmacological properties, which can enable the development of new drug prototypes with anti-inflammatory, antinociceptive, antitumor, antiviral, and antiparasitic applications. Objective: aspects, and applications of the main venom toxins (convulxin, gyroxin, crotamine, crotoxin, and their subunits). Conclusion: The authors have found that research on this snake and its toxins is still an area of focus, despite that almost a century has passed since the isolation of crotoxin. Several applications of these proteins in the development of novel drugs and bioactive substances have also been demonstrated.

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Ausência de efeito antinociceptivo decorrente da administração intravenosa de crotalfina em comparação com morfina, U50-488H ou fenilbutazona em equinos submetidos à estimulação térmica da pele íntegra

Abstract: Ausência de efeito antinociceptivo decorrente da administração intravenosa de crotalfi na em comparação com morfi na, U50-488H ou fenilbutazona em equinos submetidos à estimulação térmica da pele íntegra

Cited by 2 publications

References 28 publications

Clinical, behavioral and antinociceptive effects of crotalphine in horses

Clinical, behavioral and antinociceptive effects of crotalphine in horses

Literature Review on Crotalus durissus terrificus Toxins: From a Perspective of Structural Biology and Therapeutic Applications

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