Aurones: Synthesis and Properties

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“…A number of Aurones are isolated from several natural sources, such as Cyperaceae and Cyperus capitatus family [8][9] . These derivatives are reported for their persuasive Anti-neoplastic, antidiabetic and anti-inflammatory activities.…”

Hydrogen sulfide sensing using an aurone-based fluorescent probe

“…Aurones are a small family of natural products primarily responsible for the golden pigmentation present in plants with yellow owers such as dahlias, snapdragons, and cosmos. [46][47][48] Due to their unusual exocyclic alkene, they absorb at longer wavelengths compared to the more common avones. At the same time, this ring system is easy to synthesize in a variety of ways, particularly the acid or base catalyzed condensation of an aldehyde and a benzofuranone.…”

An Unusual Triazole Synthesis from Aurones

“…13C{1 H} NMR (75 MHz, CDCl 3 ):  = 191.9, 163.6, 141.1, 137.6, 134.8, 133.7, 129.9, 128.7, 126.9, 119.4, 118.5 (peaks for another tautomer were also observed). HRMS (EI): m/z [M + H] calcd for C 15 H 11 ClN 3 O 2 : 300.0540; found: 300.0541.…”

“…Aurones are an interesting minor sub-family of the flavonoid family of natural products. 1 Although known for some time, they have received comparatively little interest until fairly recently. Even this current interest has been fairly limited in terms of its diversity.…”

“…From aurone 19a (98.7 mg, 0.34 mmol), no chromatographic separation was needed; yield: 101 mg (89%); yellow solid; mp 127-129 °C. IR (neat):3226, 2828, 1626, 1607, 1479, 1450, 1432, 1322, 1158, 1110, 920, 845 cm -1 1. H NMR (500 MHz, CDCl 3 ):  = 11.96 (s, 1 H), 8.07 (d, J = 8.0 Hz, 1 H), 7.88 (d, J = 8.0 Hz, 2 H), 7.70 (d, J = 8.0 Hz, 2 H), 7.56 (ddd, J = 8.5, 7.5, 1.5 Hz, 1 H), 7.08 (d, J = 8.5 Hz, 1 H), 6.92 (t, J = 8.0 Hz, 1 H).…”