Aureobasidium pullulans produced β-glucan is effective to enhance Kurosengoku soybean extract induced Thrombospondin-1 expression

Muramatsu, Daisuke; Okabe, Mitsuyasu; Takaoka, Akinori; Kida, Hiroshi; Iwai, Atsushi

doi:10.1038/s41598-017-03053-9

Cited by 8 publications

(6 citation statements)

References 45 publications

(62 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Aureobasidium pullulans secrets soluble β‐glucan consisting of a β‐(1,3)‐linked glucose main chain and β‐(1,6)‐linked glucose branches. Oral administration of the A. pullulans –derived β‐glucan prevented development of fatty liver in mice on high‐fat diets 72 . β‐glucans are mainly known as immune stimulators.…”

Section: Fungi‐based Therapeutical Strategies For Liver Diseasementioning

confidence: 99%

Roles for the mycobiome in liver disease

Zeng

Schnabl

2022

Liver International

View full text Add to dashboard Cite

Liver disease, a major cause of global mortality, has been associated with dysbiosis of the intestinal microbiota (bacteria, fungi, viruses, and other microbes). Studies have associated changes in gut bacteria with pathogenesis and severity of liver disease, but the contributions of the mycobiome (the fungal populations of the gut) to health and disease have not been well studied. We review recent findings of alterations in the composition of the mycobiota in patients with liver disease and discuss the mechanisms by which these might affect pathogenesis and disease progression. Strategies to manipulate the gut mycobiota might be developed to treat or prevent liver disease.

show abstract

Section: Fungi‐based Therapeutical Strategies For Liver Diseasementioning

confidence: 99%

Roles for the mycobiome in liver disease

Zeng

Schnabl

2022

Liver International

View full text Add to dashboard Cite

show abstract

“…In addition, they contain many biologically active substances, such as isoflavone, which prevents adult diseases; saponin, which excels in preventing cancer; and lecithin, which reduces cholesterol levels. Thus, soybeans are often utilized as health products ( Muramatsu et al., 2017 ). Furthermore, soybean proteins have been used as additives to enhance the quality characteristics of meat products, and previous studies have been conducted into incorporating vegetable proteins into meat products to fulfill the role of meat or fat ( Park et al, 2020 ; Polizer et al, 2015 ; Tarté et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Effects of Using Soybean Protein Emulsion as a Meat Substitute for Chicken Breast on Physicochemical Properties of Vienna Sausage

Kang¹,

Lee²,

Kim³

2022

Food Sci Anim Resour

View full text Add to dashboard Cite

The aim of this study is to determine the effects of using emulsion manufactured with soybeans (ES) to substitute chicken breast in Vienna sausages. Four types of Vienna sausages (S1: 10% ES and 50% chicken, S2: 20% ES and 40% chicken, S3: 30% ES and 30% chicken, and S4: 40% ES and 20% chicken) for this study were made. The pH, color, proximate composition, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), microphotographs, cooking yields, and texture profile analysis of sausages were examined. The pH value of uncooked and cooked sausages increased significantly with increasing ES content (p<0.05). The crude protein contents of S2, S3, and S4 were significantly higher than that of the control (p<0.05). Furthermore, the SDS-PAGE results showed that α-conglycinin, β-conglycinin, and the acidic subunit of glycinin all increased with increasing ES content. Microphotographs revealed that increasing the ES content decreased the size of fat globules. The cooking yields of samples increased significantly with increasing ES content (p<0.05). The hardness values of ES treated samples were significantly lower than that of the control (p<0.05). Therefore, 30% substitute of chicken breast with ES can improve the quality and structure of Vienna sausage, without inducing critical defects.

show abstract

“…Fungal products might also be developed as therapies although the potential health benefits, or probiotic effects of some fungal species are known but have yet to be fully explored [ 86 ]. Only Aureobasidium pullulans obtained from administrated black yeast prevented the develop of fatty liver in mice on high-fat diets [ 99 ].…”

Section: Pro- Pre- and Symbiotic Therapy In Nafld And Sibomentioning

confidence: 99%

Small Intestinal Bacterial Overgrowth and Non-Alcoholic Fatty Liver Disease: What Do We Know in 2023?

Gudan

Kozłowska-Petriczko

Bodnarczuk³

et al. 2023

Nutrients

View full text Add to dashboard Cite

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease associated with the pathological accumulation of lipids inside hepatocytes. Untreated NAFL can progress to non-alcoholic hepatitis (NASH), followed by fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). The common denominator of the above-mentioned metabolic disorders seems to be insulin resistance, which occurs in NAFLD patients. Obesity is the greatest risk factor for lipid accumulation inside hepatocytes, but a part of the NAFLD patient population has a normal body weight according to the BMI index. Obese people with or without NAFLD have a higher incidence of small intestinal bacterial overgrowth (SIBO), and those suffering from NAFLD show increased intestinal permeability, including a more frequent presence of bacterial overgrowth in the small intestine (SIBO). The health consequences of SIBO are primarily malabsorption disorders (vitamin B12, iron, choline, fats, carbohydrates and proteins) and bile salt deconjugation. Undetected and untreated SIBO may lead to nutrient and/or energy malnutrition, thus directly impairing liver function (e.g., folic acid and choline deficiency). However, whether SIBO contributes to liver dysfunction, decreased intestinal barrier integrity, increased inflammation, endotoxemia and bacterial translocation is not yet clear. In this review, we focus on gut–liver axis and discuss critical points, novel insights and the role of nutrition, lifestyle, pre- and probiotics, medication and supplements in the therapy and prevention of both SIBO and NAFLD.

show abstract

Aureobasidium pullulans produced β-glucan is effective to enhance Kurosengoku soybean extract induced Thrombospondin-1 expression

Cited by 8 publications

References 45 publications

Roles for the mycobiome in liver disease

Roles for the mycobiome in liver disease

Effects of Using Soybean Protein Emulsion as a Meat Substitute for Chicken Breast on Physicochemical Properties of Vienna Sausage

Small Intestinal Bacterial Overgrowth and Non-Alcoholic Fatty Liver Disease: What Do We Know in 2023?

Contact Info

Product

Resources

About