Auraptene Alleviates Paclitaxel-induced Neuropathy in Mice
Zihong Cong,
Jun Wang,
Mahmoud Hashemzaei
et al.
Abstract:Background Paclitaxel administration causes peripheral neuropathy. Auraptene is a natural bioactive monoterpene with anti-inflammatory and anti-neuropathic effects that is widely used. Objectives We aimed to study auraptene effects on paclitaxel-induced neuropathy. Materials and Methods This study was comprised of two steps of evaluation of the preventive and treatment effects of auraptene in mice. In the first step, mice were randomly allocated into three groups of six animals, including the negative control … Show more
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