Auranofin attenuates Schistosoma mansoni egg-induced liver granuloma and fibrosis in mice
A.F. Atia,
N.M. Abou-Hussien,
D.M. Sweed
et al.
Abstract:Schistosomiasis is a serious tropical disease. Despite extensive research into the etiology of liver fibrosis, effective therapeutic options remain limited. This study aims to assess the effectiveness of auranofin in treating hepatic granuloma and fibrogenesis produced by Schistosoma (S.) mansoni eggs. Auranofin is a gold complex that contains thioglucose tetraacetate and triethylphosphine. Eighty BALB/c male mice were divided into four groups (n=20/group): negative control (GI), positive control (GII), and ea… Show more
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