Aujeszky's disease of sheep: Experimental studies on the excretion and horizontal transmission of the virus

Mocsári, E; Tóth, Cs.; Meder, M.; Sághy, E; Gianni, Robert

doi:10.1016/0378-1135(87)90066-6

Cited by 6 publications

(6 citation statements)

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“…Although goats are more susceptible to contagion and show more pronounced clinical manifestations, in sheep, morbidity can reach 60% [ 8 ]. This is likely due to the possibility of horizontal transmission [ 30 , 31 ]. The symptoms described in the present study were similar to those reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

Retrieving Historical Cases of Aujeszky’s Disease in Sicily (Italy): Report of a Natural Outbreak Affecting Sheep, Goats, Dogs, Cats and Foxes and Considerations on Critical Issues and Perspectives in Light of the Recent EU Regulation 429/2016

et al. 2021

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Aujeszky’s disease is caused by Suid alphaherpesvirus 1, and its main reservoir host is the pig. However, other species are also susceptible. Infection with this virus causes a severe neurological clinical picture named Aujeszky’s disease, usually accompanied by itching and death a few days after the onset of symptoms. This study reports a multi-species outbreak of Aujeszky’s disease that occurred in Sicily, which led to the death of 2 goats, 15 sheep, 2 dogs, 2 cats and 2 foxes. The diagnosis was made by culture, indirect immunofluorescence on brain samples and confirmed by biological test on rabbits. This study reports the first cases of Aujeszky’s disease in Italy in cats, goat and sheep. The finding of Aujeszky’s disease in several species in Sicily suggests a potential epizootic risk. In such areas where a multi-host system is recognised, an analysis of the risk factors should be carried out in order to develop targeted strategies for the control and eradication of the disease. The critical issues that hinder the control of Aujeszky’s disease in the studied territory and perspectives for eradication in the light of EU regulation 429/2016 are also discussed.

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Section: Discussionmentioning

confidence: 99%

Retrieving Historical Cases of Aujeszky’s Disease in Sicily (Italy): Report of a Natural Outbreak Affecting Sheep, Goats, Dogs, Cats and Foxes and Considerations on Critical Issues and Perspectives in Light of the Recent EU Regulation 429/2016

et al. 2021

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“…PRV infected sheep and goats are generally not contagious [ 63 ]. Infection usually leads to death with central nervous disorders, often with severe pruritus [ 63 , 64 , 65 , 66 ]. Although the frequency of natural infection in sheep is low, mortality rates of up to 60% due to AD can result in significant losses in sheep flocks [ 67 ].…”

Section: Aujeszky’s Disease In Mammalsmentioning

confidence: 99%

“…Small ruminants excrete very little virus; contact infections from animal to animal are not expected. However, lambs can excrete as much virus as piglets with nasal secretion just before and when clinical symptoms appear, and horizontal transmission of PRV from lambs to pigs has been demonstrated [ 63 ].…”

Section: Aujeszky’s Disease In Mammalsmentioning

confidence: 99%

“…Sheep of all ages are affected, which develop the clinical picture of central nervous irritation and paralysis [ 63 , 64 , 65 , 69 ]. The main clinical signs are fever, restlessness and movement disabilities.…”

Section: Aujeszky’s Disease In Mammalsmentioning

confidence: 99%

“…Gross pathology is generally inconspicuous involving skin injuries after facial trauma, wool-free areas of the lateral chest behind the elbow joint, abdominal wall and on the limbs, wool in the rumen, pulmonary edema with lobular interstitial pneumonia, hyperemia of the meninges, petechiae in the cervicothoracic ganglia and dilated esophagus are described [ 63 , 64 , 65 ]. Ganglioneuritis with intranuclear inclusions is rather typical, but not always present.…”

Section: Aujeszky’s Disease In Mammalsmentioning

confidence: 99%

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Comparative Pathology of Pseudorabies in Different Naturally and Experimentally Infected Species—A Review

Sehl

Teifke

2020

Pathogens

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The pseudorabies virus (PRV) is an alphaherpesvirus and the causative agent of Aujeszky’s disease (AD). PRV infects a wide range of animal species including swine as the natural host as well as ruminants, carnivores, rodents and lagomorphs. In these species, except for the pig, PRV infection causes acute, severe disease, characterized by insatiable itching, and is always lethal. Horses, chickens and non-human primates have been shown to be largely resistant to PRV infection, while disease in humans is still controversial. PRV is a pantropic virus, which preferably invades neural tissue, but also infects epithelia of various organs, whereupon multisystemic lesions may result. Although AD is mainly associated with severe pruritus, also known as “mad itch”, there are notable differences regarding infection route, clinical signs, viral distribution and lesion patterns in different animal species. In this comprehensive review, we will present clinico-pathologic findings from different species, which have been either shown to be susceptible to PRV infection or have been tested experimentally.

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Aujeszky’s Disease (Pseudorabies) in Ruminants

Wittmann¹

1989

Developments in Veterinary Virology

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Aujeszky's disease of sheep: Experimental studies on the excretion and horizontal transmission of the virus

Cited by 6 publications

References 9 publications

Retrieving Historical Cases of Aujeszky’s Disease in Sicily (Italy): Report of a Natural Outbreak Affecting Sheep, Goats, Dogs, Cats and Foxes and Considerations on Critical Issues and Perspectives in Light of the Recent EU Regulation 429/2016

Retrieving Historical Cases of Aujeszky’s Disease in Sicily (Italy): Report of a Natural Outbreak Affecting Sheep, Goats, Dogs, Cats and Foxes and Considerations on Critical Issues and Perspectives in Light of the Recent EU Regulation 429/2016

Comparative Pathology of Pseudorabies in Different Naturally and Experimentally Infected Species—A Review

Aujeszky’s Disease (Pseudorabies) in Ruminants

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