Auditory processing disorder may be present in schizophrenia and it is highly correlated with formal thought disorder

Implications for Early Diagnosis and Treatment in Schizophrenia Due to Correlation between Auditory Perceptual Deficits and Cognitive Impairment

“…The study population comprised 50 schizophrenia patients, the same who participated in our previous study [ 27 ]. No participants had a history of mental retardation, neurodevelopmental disorders, traumatic head injury, neurological disorders, or a diagnosis of alcohol or substance use disorder during the last 12 months.…”

“…In a recent study [ 27 ], we implemented an auditory processing battery, which included temporal processing, speech perception, and DL tasks, to 50 schizophrenia patients and 25 healthy controls. We also investigated possible correlations between auditory processing deficits and clinical symptoms, especially the positive symptom of formal thought disorder (FTD), which was not previously examined separately.…”

“…In brief, we discovered that [ 27 ] (1) patients with schizophrenia had significantly poorer performance than healthy controls on all auditory processing tasks, (2) the majority (64%) of schizophrenia patients were diagnosed with APD, while the vast majority (91.3%) of patients with significant FTD met the APD criteria, (3) FTD, as well as specific elements of FTD, was correlated with auditory deficits, and (4) other clinical symptoms, including delusions, were associated with auditory deficits.…”

“…In a meta-analysis of 52 studies, Bora et al (2019) [ 36 ] discovered that there are significant associations between either “positive” or “negative” FTD and impairments in multiple cognitive functions, including verbal memory, visual memory, attention, processing speed, planning, fluency, and working memory. As we have already demonstrated [ 27 ] that auditory processing deficits are highly correlated with FTD in schizophrenia, the discovery of a separate association between auditory processing and cognition could be very useful in expanding our knowledge of the underlying pathophysiological processes of the disorder.…”

العتبات الإدراکیة السمعیة لدى مرضى الفصام والاضطراب الوجدانی ثنائی القطب والأصحاء

“…3 (Domjan et al,2012;Koychev et al,2010;Moschopoulos et al,2019;Moschopoulos et al,2020;Rissling et al,2012;Turetsky et al,2009;Umbricht et al,2006 Woodruff, et al,1993;Hoff et al,1994;Reite et al, 1997;Downhill et al,2001;Keshavan et al, 2002 (Friedman et al, 2001;Force et al,2008;Hugdahl et al,2012;Kantrowitz et al,2014;Stevenson et al,2017; (Brambilla et al, 2003;Bruder et al,1994;Frumin et al, 2002;Garcia-Toro et al,2001 Johnson & Crockett,1982;Nehra et al, 2006;Starkstein et al, 1991 (Seidman et al,2003;Barrett et al,2009;Sánchez-Morla et al,2009 ;Hartberg et al,2011…”