Auditory orienting and inhibition of return in schizophrenia: A functional magnetic resonance imaging study

Abbott, Christopher; Merideth, Flannery; Ruhl, David A.; Yang, Zhen; Clark, Vincent P.; Calhoun, Vince D.; Hanlon, Faith M.; Mayer, Andrew R.

doi:10.1016/j.pnpbp.2011.12.011

Cited by 7 publications

(4 citation statements)

References 77 publications

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“…For Task 1 hemodynamic response functions were explicitly modeled for single (S1) and pairs (S1 + S2) of identical (IT; “gating-out” redundant information) or non-identical (NT; “gating-in” novel information) tones (Mayer et al 2013 ). For Task 2, cues presented to the left or right ear (100 ms, 2000 Hz tone pip) correctly predicted the location of the targets (100 ms, 1000 Hz tone pip) in 50% of the trials (Abbott et al 2012 ). Participants pressed a button with their right middle finger for tones on the right headphone and a button with their right index finger for tones on their left.…”

Section: Methods and Resultsmentioning

confidence: 99%

Multimodal Neuroimaging in Schizophrenia: Description and Dissemination

et al. 2017

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In this paper we describe an open-access collection of multimodal neuroimaging data in schizophrenia for release to the community. Data were acquired from approximately 100 patients with schizophrenia and 100 age-matched controls during rest as well as several task activation paradigms targeting a hierarchy of cognitive constructs. Neuroimaging data include structural MRI, functional MRI, diffusion MRI, MR spectroscopic imaging, and magnetoencephalography. For three of the hypothesis-driven projects, task activation paradigms were acquired on subsets of ~200 volunteers which examined a range of sensory and cognitive processes (e.g., auditory sensory gating, auditory/visual multisensory integration, visual transverse patterning). Neuropsychological data were also acquired and genetic material via saliva samples were collected from most of the participants and have been typed for both genome-wide polymorphism data as well as genome-wide methylation data. Some results are also presented from the individual studies as well as from our data-driven multimodal analyses (e.g., multimodal examinations of network structure and network dynamics and multitask fMRI data analysis across projects). All data will be released through the Mind Research Network’s collaborative informatics and neuroimaging suite (COINS).Electronic supplementary materialThe online version of this article (doi:10.1007/s12021-017-9338-9) contains supplementary material, which is available to authorized users.

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Section: Methods and Resultsmentioning

confidence: 99%

Multimodal Neuroimaging in Schizophrenia: Description and Dissemination

et al. 2017

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“…Fifty-seven healthy adult volunteers were recruited to participate in the current study through community advertisements. Data from a subset of the current cohort were previously published in a study examining orienting in patients with schizophrenia ( Abbott et al, 2012 ). One participant was identified as a motion outlier (more than three times the interquartile range on 2 of 6 framewise displacement parameters) and was removed from subsequent analyses.…”

Section: Methodsmentioning

confidence: 99%

From Behavioral Facilitation to Inhibition: The Neuronal Correlates of the Orienting and Reorienting of Auditory Attention

Hanlon

Dodd

Ling

et al. 2017

Front. Hum. Neurosci.

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Successful adaptive behavior relies on the ability to automatically (bottom-up) orient attention to different locations in the environment. This results in a biphasic pattern in which reaction times (RT) are faster for stimuli that occur in the same spatial location (valid) for the first few hundred milliseconds, which is termed facilitation. This is followed by faster RT for stimuli that appear in novel locations (invalid) after longer delays, termed inhibition of return. The neuronal areas and networks involved in the transition between states of facilitation and inhibition remain poorly understood, especially for auditory stimuli. Functional magnetic resonance imaging (fMRI) data were therefore collected in a large sample of healthy volunteers (N = 52) at four separate auditory stimulus onset asynchronies (SOAs; 200, 400, 600, and 800 ms). Behavioral results indicated that facilitation (valid RT < invalid RT) occurred at the 200 ms SOA, with inhibition of return (valid RT > invalid RT) present at the three longer SOAs. fMRI results showed several brain areas varying their activation as a function of SOA, including bilateral superior temporal gyrus, anterior thalamus, cuneus, dorsal anterior cingulate gyrus, and right ventrolateral prefrontal cortex (VLPFC)/anterior insula. Right VLPFC was active during a behavioral state of facilitation, and its activation (invalid – valid trials) further correlated with behavioral reorienting at the 200 ms delay. These results suggest that right VLPFC plays a critical role when auditory attention must be quickly deployed or redeployed, demanding heightened cognitive and inhibitory control. In contrast to previous work, the ventral and dorsal frontoparietal attention networks were both active during valid and invalid trials across SOAs. These results suggest that the dorsal and ventral networks may not be as specialized during bottom-up auditory orienting as has been previously reported during visual orienting.

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“…Due to its capability of producing excellent quality and high-resolution images, allowing a fast scan time as well as no need of radiochemicals, MRI has been proved as the most important modality in both clinical and research settings. [247][248][249][250][251][252][253][254][255][256][257] Therefore, integrating this advanced technique into cell (especially tumor cell) imaging will greatly boost the development of diagnostics.…”

Section: Cell Imagingmentioning

confidence: 99%

Graphene and its derivatives for cell biotechnology

Yang

Yao

Duan

2013

Analyst

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Every few years, a novel material with salient and often unique properties emerges and attracts both academic and industrial interest from the scientific community. The latest blockbuster is graphene, an increasingly important nanomaterial with atomically thin sheets of carbon, which has become a shining star and has shown great promise in the field of material science and nanotechnology. In recent years, it has changed from being the exclusive domain of physicists to the new passion of chemists and biologists. Graphene and its derivatives are now at the forefront of nearly every rapidly developing field of science and engineering, including biochemistry, biomedicine and certain cutting-edge interdisciplines that have intense popularity. The aim of this review is, firstly, to provide readers with a comprehensive, systematic and in-depth prospective of graphene's band structure and properties, and secondly, to concentrate on the recent progress in producing graphene-based nanomaterials, including mechanical exfoliation, chemical vapor deposition, plasma enhanced chemical vapor deposition, chemical reduction of graphene oxide, total organic synthesis, electrochemical synthesis and other fabrication strategies widely accepted by research scientists. At the same time, important definitions related to graphene are also introduced. The focus of this Tutorial Review is to emphasize the current situation and significance of using this new kind of two-dimensional material in the hot and emerging fields that are closely related to human life quality, for instance, cell biochemistry, bioimaging along with other frontier areas. Finally, the latest developments and possible impact that affect the heart of the whole scientific community have been discussed. In addition, the future trends along with potential challenges of this rapidly rising layered carbon have been pointed out in this paper.

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Auditory orienting and inhibition of return in schizophrenia: A functional magnetic resonance imaging study

Cited by 7 publications

References 77 publications

Multimodal Neuroimaging in Schizophrenia: Description and Dissemination

Multimodal Neuroimaging in Schizophrenia: Description and Dissemination

From Behavioral Facilitation to Inhibition: The Neuronal Correlates of the Orienting and Reorienting of Auditory Attention

Graphene and its derivatives for cell biotechnology

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