Audit of pulse oximetry screening for critical congenital heart disease (CCHD) in newborns

Lightfoot, Marnie; Hough, Philip; Hudak, Alan; Gordon, Michelle; Barker, Sarah; Meeder, Robert; Colpitts, Melanie; Roberts, Gwendolyn; Smith, William G.

doi:10.1093/pch/pxx091

Cited by 5 publications

(5 citation statements)

References 6 publications

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“…In one recent report from a center where the practice of routine pulse oximetry screening for congenital heart disease was adopted and then audited, compliance with their protocol was 88%, which is good but not optimal. 25 The association of late diagnosis with MACE after repair of truncus arteriosus in our study and the aforementioned data on the benefits of routine pulse oximetry screening for congenital heart disease support the further expansion of this practice and the establishment of infrastructure at the local level to ensure that these programs are operating appropriately.…”

Section: Discussionsupporting

confidence: 73%

Characteristics and operative outcomes for children undergoing repair of truncus arteriosus: A contemporary multicenter analysis

Mastropietro

Amula

Sassalos

et al. 2019

The Journal of Thoracic and Cardiovascular Surgery

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Objective: We sought to describe characteristics and operative outcomes of children who underwent repair of truncus arteriosus and identify risk factors for the occurrence of major adverse cardiac events (MACE) in the immediate postoperative period in a contemporary multicenter cohort.Methods: We conducted a retrospective review of children who underwent repair of truncus arteriosus between 2009 and 2016 at 15 centers within the United States. Patients with associated interrupted or obstructed aortic arch were excluded. MACE was defined as the need for postoperative extracorporeal membrane oxygenation, cardiopulmonary resuscitation, or operative mortality. Risk factors for MACE were identified using multivariable logistic regression analysis and reported as odds ratios (ORs) with 95% confidence intervals (CIs).Results: We reviewed 216 patients. MACE occurred in 44 patients (20%) and did not vary significantly over time. Twenty-two patients (10%) received postoperative extracorporeal membrane oxygenation, 26 (12%) received cardiopulmonary resuscitation, and 15 (7%) suffered operative mortality. With multivariable logistic regression analysis (which included adjustment for center effect), factors independently associated with MACE were failure to diagnose truncus arteriosus before discharge from the nursery (OR, 3.1; 95% CI, 1.3-7.4), cardiopulmonary bypass duration>150 minutes (OR, 3.5; 95% CI, 1.5-8.5), and right ventricle-topulmonary artery conduit diameter >50 mm/m 2 (OR, 4.7; 95% CI, 2.0-11.1).

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Section: Discussionsupporting

confidence: 73%

Characteristics and operative outcomes for children undergoing repair of truncus arteriosus: A contemporary multicenter analysis

Mastropietro

Amula

Sassalos

et al. 2019

The Journal of Thoracic and Cardiovascular Surgery

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“…Our results showed that PO had a sensitivity of 100%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 100% in comparison to Echocardiography as a gold standard test. In line with our results Lightfoot et al, the specificity was 99.4% while the sensitivity were not applicable (16). In contrary Danworapong et al found the sensitivity of PO was 42.86% and a specificity of 99.96% (17), the sensitivity was lower than that in our studies because of a high percentage of cases diagnosed as coarctation of the aorta (COA) (57.1%) in this study; it is known that COA has a low sensitivity of POS for CCHD (36%-53.3%).…”

Section: Discussionsupporting

confidence: 86%

Pulse oximetry for diagnosis of Critical Congenital Heart Disease

2021

Aswan University Medical Journal

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Background: Critical Congenital heart disease (CCHD) includes severe disorders that require early identification to enhance early detection of CCHD, and early interference to optimize neonatal outcomes. Objective: To evaluate the accuracy of pulse oximeter in detecting CCHD in neonates. Patients and methods: all neonates delivered at Aswan University Hospital were recruited. The screening was performed by (Pulse oximetry) PO and echocardiography (ECHO) between 24 and 72 hours of age. Results: Among the 100 screened newborn, it was found that 5 true positive and 95 true negative cases. PO test for CCHD had a sensitivity of 100%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 100%. Conclusion: PO is a noninvasive and harmless, practicable tool to screen CCHD and diagnose clinically undetectable CCHD in newborns.

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“…Furthermore, Name of the author [25] discovered that Pulse oximetry (PO) offers 100% sensitivity, 100% specificity, 100% positive predictive value, and 100% negative predictive value-when compared to echocardiography, the gold standard test. That was by Name of the author [26] reported that the sensitivity was not applicable, and the specificity was 99.4%. On the other hand, Name of the author [27] discovered that the specificity was 99.96% and the sensitivity of PO was 42.86%.…”

Section: Discussionmentioning

confidence: 98%

Neonatal Pulse Oximetry Screening for Congenital Heart Disease

El Bakry,

Abd el Hie,

Amin

et al. 2024

Benha Medical Journal

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Background: Lower respiratory tract infections, sepsis, and congenital heart disease are still the main causes of new-born death, but most of these issues are curable with early detection and treatment. It has been established that pulse oximetry screening (POS) is a non-invasive investigation that can identify 50-70% of congenital heart defects (CHDs) that have not been identified before. The aim of this study is to count the number of participants with congenital heart disease who were found through early screening-using pulse oximetry. Methods: A prospective study was conducted on new-borns patients with congenital heart disease -who admitted to the well-baby nursery and neonatal intensive care unit (NICU) of implementation-was performed at 2 tertiaries hospitals, (Dubai hospital in United Arab Emirates and Benha university hospital in Egypt) on all deliveries born from June 2014 through December 2016. Results: there were 41 patients had pulse oximetry≤90 (27.7%), 73 patients had pulse oximetry≤92 (49.3%) and 114 patients had pulse oximetry≤95 (77.0%). Also, the initial pulse oximetry different was ranged (3.00-6.00) with mean (3.88±1.02) and the second pulse oximetry different was ranged (2.00-7.00) with mean (4.01±1.22). Conclusion: Even in the first hour of life, oxygen saturations were found to be abnormal in the majority of CCHD patients. The proportions of anomalous results were highest with the highest oxygen saturation threshold (95%).

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Audit of pulse oximetry screening for critical congenital heart disease (CCHD) in newborns

Abstract: The current study shows that screening was successfully implemented in a Canadian hospital, with high specificity (99.4%) and good compliance (88%). Reasons for non-acceptance of screening by midwives need to be addressed.

Cited by 5 publications

References 6 publications

Characteristics and operative outcomes for children undergoing repair of truncus arteriosus: A contemporary multicenter analysis

Characteristics and operative outcomes for children undergoing repair of truncus arteriosus: A contemporary multicenter analysis

Pulse oximetry for diagnosis of Critical Congenital Heart Disease

Neonatal Pulse Oximetry Screening for Congenital Heart Disease

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