Audiotympanometric Findings in Myasthenia Gravis

Morioka, Wilfred T.; Neff, Palmer A.; Boisseranc, Thomas E.; Hartman, Paul W.; Cantrell, Robert W.

doi:10.1001/archotol.1976.00780090053007

Cited by 14 publications

(10 citation statements)

References 5 publications

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“…The signs of Eustachian tube dysfunction found during the early stages in the two most severely affected patients were comparable to those reported in several other neuromuscular diseases (Morioka, Neff, Boisseranc, Hartmen, & Cantrell, 1976;Neff, Morioka, Sample, & Cantrell, 1980). However, these findings cannot be unequivocally attributed to failure of neuromuscular transmission, as medical intervention procedures and a variety of complications may have been contributing factors.…”

Section: Discussionsupporting

confidence: 86%

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Audiologic Findings in Botulism Poisoning

Pijl

1991

Ear and Hearing

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Botulism poisoning results in a presynaptic failure of neuromuscular transmission, and may be expected to impair Eustachian tube and stapedius reflex function. The audiologic findings in five normal-hearing patients with type A botulism poisoning are presented. Results were varied. Two patients demonstrated type B or C tympanograms during the early stages, while three with normal middle ear function demonstrated marked bilateral or unilateral stapedius reflex threshold elevation. One patient had a reversible reflex decay, and the superimposition of a second stimulus upon the first resulted in complete recovery of reflex amplitude. A number of possible pathophysiological mechanisms are discussed (Ear Hear 12 4:281-286).

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Section: Discussionsupporting

confidence: 86%

“…Hearing threshold changes and hyperacusis have occasionally been reported in patients with abnormalities of the stapedius reflex (Morioka et al, 1976). None of the patients in our series complained of hyperacusis, although some reported a general increase in irritability involving, also, other sensory modalities.…”

Section: Discussionmentioning

confidence: 37%

Audiologic Findings in Botulism Poisoning

Pijl

1991

Ear and Hearing

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“…Morioka et al [8] reported that MG pa tients treated with anti-cholinesterase dem onstrated an increase of around 10 dB in the pure tone thresholds at 1,000-4,000 Hz. In the present research, pure-tone audiometry was carried out in 2 MG patients before and after anti-cholinesterase was administered.…”

Section: Discussionmentioning

confidence: 99%

“…However, no changes in the pure tone thresh olds were observed. Morioka et al [8] re ported that in patients who suffered cither myasthenic crisis (under-dosage) or choliner gic crisis (overdosage), a tympanogram re vealed the existence of negative middle ear pressure because of the weakness of the ten sor veli palatini muscle. Nevertheless, in the present study, none of the 11 MG patients demonstrated negative middle ear pressure peaks of below -50 mm H20 on tympanograms.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Stapedial Reflex in Neuromuscular Diseases

Yamane¹,

Nomura²

1984

ORL

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An impedance audiometric analysis of the stapedial reflex was carried out in 17 patients with motor neuron disease (MND), 11 with myasthenia gravis (MG), and 3 myotonic dystrophy (MD). The features examined were the threshold and latency parameters and the response pattern of the reflex. All groups had mean reflex thresholds within normal limits (80–90 dB hearing level). The MND group showed a lengthened mean reflex latency (L₁). The MG group showed an unstable response pattern to 10-second tone stimuli and a lengthened L₁. Half the group demonstrated abnormal decay of the reflex. The MD group showed a reduction in the growth of averaged reflex in response to stimuli with short interstimulus intervals (2.6 s) and the L₁and C₅₀ were lengthened.

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“…Available evidence suggests that hyperacusis may follow functional changes within the central nervous system and may be related to increased gain in the central auditory pathways and to increased anxiety or emotional response to sound 5 . Hyperacusis has been reported in some systemic conditions and syndromes [6][7][8][9][10][11][12][13][14][15][16][17][18] , although most cases of hyperacusis have unknown cause 19,20 .…”

Section: Introductionmentioning

confidence: 99%

Hyperacusis in Children: A Preliminary Study on the Effects of Hypersensitivity to Sound on Speech and Language

Ralli

Greco

Altissimi

et al. 2018

The International Tinnitus Journal

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There is a growing awareness that children may experience hyperacusis, a condition that is often associated with behavioral and developmental disorders. This preliminary study was aimed to investigate the effects of hyperacusis alone on various components of speech and language in children without developmental disorders. This study was conducted on 109 children aged between 4 and 7 years attending kindergarten and primary school. Hyperacusis was assessed through behavioral observation of children and questionnaires for parents. Different components of speech and language were assessed through specific tests. Hyperacusis was diagnosed in fifteen children (13.8%); ten (66.7%) were attending primary school and five (33.3%) kindergarten. A significant difference between children with and without hyperacusis was found for tests evaluating the average number of words in a sentence and phonemic fluency; older children appeared to have more difficulties. Several differences in education profiles were found: parents of children with hyperacusis spent less time with their children compared to parents of children without hyperacusis. Our preliminary results suggest some difficulties in lexical access and the use of shorter sentences by children with hypersensitivity to sound; however, the small size of our sample and the largely unknown interactions between hyperacusis and developmental disorders suggest caution when interpreting these results. Further studies on larger samples are necessary to gain additional knowledge on the effects of hyperacusis on speech and language in children without developmental disorders.

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Audiotympanometric Findings in Myasthenia Gravis

Cited by 14 publications

References 5 publications

Audiologic Findings in Botulism Poisoning

Audiologic Findings in Botulism Poisoning

Analysis of Stapedial Reflex in Neuromuscular Diseases

Hyperacusis in Children: A Preliminary Study on the Effects of Hypersensitivity to Sound on Speech and Language

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