Audiological evidence of therapeutic effect of steroid treatment in neuromyelitis optica with hearing loss

Probable neuromyelitis optica spectrum disorder presenting with recurrent cranial neuropathy

“…Brain MRI showed meningeal and eighth cranial nerve enhancement; therefore her palsy of the eighth cranial nerve might have had a peripheral origin due to pachymeningitis. Although no focal cavernous sinus lesion has been reported in NMO so far, in light of the previously reported cases, it seems reasonable to assume that a cavernous sinus lesion by focal pachymeningitis could occur as a result of NMOSD …”

“…In NMOSD, hypertrophic pachymeningitis has also been recognized, without and with peripheral cochleovestibular (8th) cranial nerve involvement. Among these, Bonnan and Cabre reported a 53‐year‐old woman with NMOSD with right deafness and vertigo (8th) .…”

“…Because of the brainstem lesion, NMOSD occasionally shows dysfunction of the extraocular muscles (diplopia) and other cranial nerves (dysphagia, dysarthria etc.). More recently, hypertrophic pachymeningitis has been recognized in NMOSD, without and with peripheral cochleovestibular (8th) cranial nerve involvement. Here, we add a case of a young woman who presented with recurrent oculomotor (3rd) and abducens (6th) nerve palsy due most probably to a cavernous sinus lesion from probable NMOSD.…”

Sudden Sensoryneural Hearing Loss as a Rare Attack Type in Multiple Sclerosis

“…However, it could be a challenging condition if it was the presenting manifestation of MS or another neurological disorder (5,6). Hearing loss was also declared in other demyelinating disorders such as neuromyelitis optica (7). For this reason, patients between the ages of 10 to 50 (most frequent ages for demyelinating disorders) should be referred to a Neurologist after the more common causes of hearing loss such as Meniere disease, ototoxic drugs, diabetes etc.…”

The Clinical and Treatment Characteristics of Neuromyelitis Optica. Summary of the Doctoral Thesis

“…have been reported ). Several reports, often accidental case reports, on other NMO symptoms such as narcolepsy, hypothermia, hearing loss, severe pain, tonic spasms, neuropathic pruritus etc can also be found, thought whether they are characteristic for NMO is yet to be studied (Baba, Nakashima et al 2009, Kanbayashi, Shimohata et al 2009, Sato and Fujihara 2011, Suzuki, Nakamura et al 2012, Nakano, Dei et al 2014,Jarius, Lauda et al 2013, Gratton, Amjad et al 2014, Takanashi, Misu et al 2014, El Otmani, Dany et al 2015, Wang, Qi et al 2015, Wingerchuk, Hogancamp et al 1999, Kim, Go et al 2012, Usmani, Bedi et al 2012, Abaroa, Rodriguez-Quiroga et al 2013.…”