Au@Ag@ZIF-8 multifunction probe with internally o-phenylenediamine encoding for the colorimetric, fluorescence, and SERS multi-mode optical detection of reactive sulfur species

Zhou, Xia; Lin, Xiaoling; Huang, Haiqiu; Li, Ping; Wu, Jia‐Min; Huang, Xueqin; Cai, Huaihong; Han, Hai; Zheng, Junxia; Zhou, Haibo

doi:10.1016/j.snb.2022.131762

Cited by 9 publications

(5 citation statements)

References 43 publications

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“…A growing demand for early cancer diagnosis has promoted the development of SERS-based multimodal sensing platform. [174] Recently, Gao et al designed a triple-mode sensing system based on SERS, colorimetric, and fluorescence mode for the determinate of RNA in SARS-CoV-2 virus, relying on the specificity between RNA and Cy3-labelled DNA and the salttriggered aggregation of AuNPs (Figure 9A). Using this a trimodal sensor, the LOD for SERS, colorimetric, and fluorescent detection in simulated samples were determined to be down to 395 fM, 259 fM, and 160 fM, respectively.…”

Section: Hybrid Biosensors Of Sers and Other Modesmentioning

confidence: 99%

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Recent Research Progress of Surface‐Enhanced Raman Scattering Dominated Analysis Strategies in Early Diagnosis of Diseases

Chen

Zheng

Tang

et al. 2023

Chemistry An Asian Journal

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Timely and powerful diagnostic means can achieve better therapeutic effects, reduce disease torment, and improve survival rate. As a powerful non‐invasive spectroscopy technology, surface‐enhanced Raman scattering (SERS) have testified to be a great potential candidate for extensive early clinical disease diagnosis. In recent years, the introduction of SERS label, combined with other analysis modes or artificial intelligence, and the emergence of miniaturized devices have made SERS technology more advantageous in early diagnosis of diseases. This review focuses on the research progress of SERS dominated analytical strategies in the field of early disease diagnosis in the past five years. The main content includes the application of label‐free SERS detection; the construction of label SERS methodologies for various disease markers; SERS dominated multimode early disease diagnosis strategies; integration of SERS and artificial intelligence; portable Raman equipment and SERS imaging; and opportunities and trends for SERS diagnostic technology in the future.

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Section: Hybrid Biosensors Of Sers and Other Modesmentioning

confidence: 99%

“…A growing demand for early cancer diagnosis has promoted the development of SERS‐based multimodal sensing platform [174] . Recently, Gao et al.…”

Section: Multimode Analysis Strategy For Cancer Diagnosismentioning

confidence: 99%

Recent Research Progress of Surface‐Enhanced Raman Scattering Dominated Analysis Strategies in Early Diagnosis of Diseases

Chen

Zheng

Tang

et al. 2023

Chemistry An Asian Journal

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“…o -Phenylenediamine ( o PD), as a common chromogen substrate, can be easily oxidized to o PD polymers, which have been widely used in fluorescent sensing for their good biocompatibility and strong fluorescence. ,,,, Most interestingly, the aggregation process and morphology of o PD polymers can be tuned by controlling the reaction conditions. ,, However, the photothermal property of o PD polymers has not been reported thus far. These inspire us to prepare o PD cascade polymers with an appropriate MOF as a nanozyme and study the possible fluorescent–photothermal dual properties of o PD cascade polymers.…”

Section: Introductionmentioning

confidence: 99%

“…10,26,29,31,32 Most interestingly, the aggregation process and morphology of oPD polymers can be tuned by controlling the reaction conditions. 29,31,32 However, the photothermal property of oPD polymers has not been reported thus far. These inspire us to prepare oPD cascade polymers with an appropriate MOF as a nanozyme and study the possible fluorescent−photothermal dual properties of oPD cascade polymers.…”

Section: ■ Introductionmentioning

confidence: 99%

In Situ Formation of o-Phenylenediamine Cascade Polymers Mediated by Metal–Organic Framework Nanozymes for Fluorescent and Photothermal Dual-Mode Assay of Acetylcholinesterase Activity

Wei

et al. 2022

Anal. Chem.

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A fluorescent and photothermal dual-mode assay method was established for the detection of acetylcholinesterase (AChE) activity based on in situ formation of o-phenylenediamine (oPD) cascade polymers. First, copper metal−organic frameworks of benzenetricarboxylic acid (Cu-BTC) were screened out as nanozymes with excellent oxidase-like activity and confinement catalysis effect. Then, an ingenious oPD cascade polymerization strategy was proposed. That is, oPD was oxidized by Cu-BTC to oPD oligomers with strong yellow fluorescence, and oPD oligomers were further catalyzed to generate J-aggregation, which promotes the formation of oPD polymer nanoparticles with a high photothermal effect. By utilizing thiocholine (enzymolysis product of acetylthiocholine) to inhibit the Cu-BTC catalytic effect, AChE activity was detected through the fluorescence−photothermal dual-signal change of oPD oligomers and polymer nanoparticles. Both assay modes have low detection limitation (0.03 U L −1 for fluorescence and 0.05 U L −1 for photothermal) and can accurately detect the AChE activity of human serum (recovery 85.0−111.3%). The detection results of real serum samples by fluorescent and photothermal dual modes are consistent with each other (relative error ≤ 5.2%). It is worth emphasizing that this is the first time to report the high photothermal effect of oPD polymers and the fluorescence−photothermal dual-mode assay of enzyme activity.

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“…In the biochemical analysis and detection system, the multifunctional integrated repeatable operating platform is always the goal scholars are keen to pursue [ 1 , 2 ]. For example, several key steps in single cell analysis (such as cell capture [ 3 ], arrangement [ 4 ], separation [ 5 ], and other operations) are integrated on one platform to realize free switching of multiple functions.…”

Section: Introductionmentioning

confidence: 99%

A Novel Detachable, Reusable, and Versatile Acoustic Tweezer Manipulation Platform for Biochemical Analysis and Detection Systems

Liu

Zhang

et al. 2022

Biosensors

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Multifunctional, integrated, and reusable operating platforms are highly sought after in biochemical analysis and detection systems. In this study, we demonstrated a novel detachable, reusable acoustic tweezer manipulation platform that is flexible and versatile. The free interchangeability of different detachable microchannel devices on the acoustic tweezer platform was achieved by adding a waveguide layer (glass) and a coupling layer (polydimethylsiloxane (PDMS) polymer film). We designed and demonstrated the detachable multifunctional acoustic tweezer platform with three cell manipulation capabilities. In Demo I, the detachable acoustic tweezer platform is demonstrated to have the capability for parallel processing and enrichment of the sample. In Demo II, the detachable acoustic tweezer platform with capability for precise cell alignment is demonstrated. In Demo III, it was demonstrated that the detachable acoustic tweezer platform has the capability for the separation and purification of cells. Through experiments, our acoustic tweezer platform has good acoustic retention ability, reusability, and stability. More capabilities can be expanded in the future. It provides a simple, economical, and multifunctional reusable operating platform solution for biochemical analysis and detection systems.

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Au@Ag@ZIF-8 multifunction probe with internally o-phenylenediamine encoding for the colorimetric, fluorescence, and SERS multi-mode optical detection of reactive sulfur species

Cited by 9 publications

References 43 publications

Recent Research Progress of Surface‐Enhanced Raman Scattering Dominated Analysis Strategies in Early Diagnosis of Diseases

Recent Research Progress of Surface‐Enhanced Raman Scattering Dominated Analysis Strategies in Early Diagnosis of Diseases

In Situ Formation of o-Phenylenediamine Cascade Polymers Mediated by Metal–Organic Framework Nanozymes for Fluorescent and Photothermal Dual-Mode Assay of Acetylcholinesterase Activity

A Novel Detachable, Reusable, and Versatile Acoustic Tweezer Manipulation Platform for Biochemical Analysis and Detection Systems

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