Atypische Mykobakteriose der Haut durch Mycobacterium abscessus bei einer immunkompetenten Frau

Nenoff, Pietro; Uhlemann, Ria; Grünewald, Thomas; Nenning, H; Grunewald, Sonja; Paasch, Uwe

doi:10.1007/s00105-007-1321-1

Cited by 4 publications

(3 citation statements)

References 29 publications

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“…The atypical mycobacterioses, including those due to Mycobacterium marinum , M. abscessus and M. ulcerans , are less commonly included in the differential diagnosis of sarcoidosis, but they must not be completely excluded 42,43 . The morphology of any single lesion must be carefully observed.…”

Section: Aetiopathogenetic Aspectsmentioning

confidence: 99%

Sarcoidosis of the skin – A dermatological puzzle: important differential diagnostic aspects and guidelines for clinical and histopathological recognition

Tchernev¹,

Nenoff³

et al. 2010

Acad Dermatol Venereol

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Sarcoidosis of the skin may have an extremely heterogeneous clinical presentation, so that the definitions of 'great imitator' and 'clinical chameleon' have long been used. There is, in fact, a large group of skin diseases that can enter the differential diagnosis with cutaneous sarcoid manifestations, either clinically or/and pathologically. As the clinical consequences and the prognosis of these groups of diseases are often very different, it is important to correctly plan the diagnostic workup. The diagnostic process in this case often presents a challenge as no single test is sufficiently specific, so that a certain diagnosis can be only made in the presence of a compatible clinical and radiographic picture, along with histopathological evidence of non-necrotizing, epithelioid cell granulomas, and exclusion of other potential aetiologies. For practical reasons, four main groups of skin conditions capable of mimicking sarcoidosis can be identified: (i) transmissible, infectious diseases; (ii) allergic and immunological manifestations of various aetiologies; (iii) granulomatous diseases of various aetiologies; and (iv) lymphomas and pseudolymphomas. The aim of this article is to describe the main clinical and histopathological findings of such disease entities, and to discuss the role of those features (morphological, pathological and laboratory) that can help distinguish them from sarcoidosis of the skin.

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Section: Aetiopathogenetic Aspectsmentioning

confidence: 99%

Sarcoidosis of the skin – A dermatological puzzle: important differential diagnostic aspects and guidelines for clinical and histopathological recognition

Tchernev¹,

Nenoff³

et al. 2010

Acad Dermatol Venereol

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“…Erst die weitere histologische, mikrobiologische und molekularbiologische Diagnostik erbrachte die Diagnose einer Infektion durch M. abscessus. Die Behandlung mit Clarithromycin und Rifabutin, später mit der Kombination Ethambutol, Minocyclin, Clofazimin und Azithromycin war erfolgreich [50].…”

Section: Leishmaniose Der Hautunclassified

Haut- und Weichgewebe-Infektionen durch nicht-tuberkulöse Mykobakterien: Ätiologie, Epidemiologie, Pathogenese, Klinik, Diagnostik, differenzialdiagnostische Aspekte und Empfehlungen für die Therapie

Nenoff¹,

Tchernev

Paasch

et al. 2011

Wien Med Wochenschr

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Non-tuberculous mycobacteria are rarely responsible for skin and soft tissue infections. These infections are caused by different mycobacterial species originating from the environment (water, soil, plants, and animals). Various factors influence the clinical manifestation of the cutaneous infection: the immunological situation of the patient, the degree of cutaneous impairment, and the extent of the contact with the contaminated environment. The clinical manifestation is non-specific and often the cause of extensive diagnostic activities. The diagnosis is based on the cultural detection of the causative pathogen. The management of these skin and subcutaneous infections is a challenge for each physician. The treatment comprises administration of several antibiotics and antituberculosis drugs for many months. Surgical procedures are necessary in some patients.

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“…Chronische Wunden am Unterschenkel -Ulcera crurahaben vielfältige Ursachen, an erster Stelle ist an eine venöse Genese zu denken, darüber hinaus an ein arteriosklerotisch bedingtes Ulkus, Diabetes mellitus mit diabetischem Fußsyndrom und Malum perforans (in der Regel im Fußbereich), bakterielle Infektionen, z. B. Mykobakterien-Infektionen [1], Tumoren, z. B. Plattenepithel-oder Basalzellkarzinome der Haut des Unterschenkels [2,3], ein entzündliches Geschehen, z.…”

unclassified

Posttraumatisches Ulcus cruris – erfolgreiches biochirurgisches Débridement mitLucilia-sericata-Larven

Nenoff¹,

Herrmann²,

Gerlach³

et al. 2010

Akt Dermatol

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Atypische Mykobakteriose der Haut durch Mycobacterium abscessus bei einer immunkompetenten Frau

Cited by 4 publications

References 29 publications

Sarcoidosis of the skin – A dermatological puzzle: important differential diagnostic aspects and guidelines for clinical and histopathological recognition

Sarcoidosis of the skin – A dermatological puzzle: important differential diagnostic aspects and guidelines for clinical and histopathological recognition

Haut- und Weichgewebe-Infektionen durch nicht-tuberkulöse Mykobakterien: Ätiologie, Epidemiologie, Pathogenese, Klinik, Diagnostik, differenzialdiagnostische Aspekte und Empfehlungen für die Therapie

Posttraumatisches Ulcus cruris – erfolgreiches biochirurgisches Débridement mitLucilia-sericata-Larven

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