Atypical Surgical Site Infection After Mohs Micrographic Surgery in an Immunocompetent Individual

Soh, Jonathan; Ibrahim, Sherrif F.; Tausk, Francisco

doi:10.1097/dss.0000000000001637

Cited by 1 publication

(1 citation statement)

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“…There is a theoretical risk of wound complications like infection or other insults if neglected. [34][35][36] Complex wounds can involve extensive wound care which may be taxing for patients or their caregivers, however if the patient is able to perform good wound care with frequent dressing changes and wound cleansing, infection can often be avoided. 21,[37][38][39][40][41] Delayed reconstruction comes with its own set of benefits.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Time to Mohs Reconstruction: A Systematic Review Comparing Complication Rates between Immediate and Delayed Repair

et al. 2023

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Background: Several known factors affect outcomes of Mohs facial defect reconstruction; however, the effect of repair timing on outcomes is ill-defined. Objective: To determine postoperative complication rates between immediate and delayed repair of Mohs facial defects. Design/Methods: Preferred Reporting Items of Systematic Reviews and Meta-Analyses guidelines were used. Articles were selected using PICO format – population: Mohs facial defect patients, intervention: defect repair, comparator: immediate (<24 hours) or delayed (>24 hours) repair, outcome: complication rate. PubMed/Medline (1946-2020), EMBASE (1947-2020), Scopus (1823-2020), Web of Science (1900-2020), Cochrane Library, and Clinicaltrials.gov were searched. Two independent reviewers screened abstracts; those in English with human subjects reporting repair timing and complication rates were included. Results: Search criteria yielded 6649 abstracts; 233 qualified for review. Data were gathered from six studies; they alone contained comparative data meeting inclusion criteria. While many well-written studies were encountered, reported results varied widely. A statistically sound meta-analysis could not be completed due large heterogeneity between studies, biasing the analysis towards the largest weighted study. Conclusions: Clinically important differences may exist between immediate and delayed Mohs reconstruction, but small study numbers, large heterogeneity, and lack of standardized outcome measures limit definitive conclusions. More studies are needed to perform appropriate meta-analyses, including studies using standardized methods of reporting Mohs outcome data.

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