Atypical psoriasis

Ingen‐Housz‐Oro, Saskia; Foulet, F.; Chosidow, Olivier

doi:10.1136/bmj.h5510

Cited by 3 publications

(6 citation statements)

References 20 publications

(21 reference statements)

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“…Cutaneous T-cell lymphoma (CTCL) incorporates a heterogenous group of lymphoproliferative disorders characterized by clonal expansions of post-thymic T-cells that subsequently infiltrate the skin. [1][2][3][4] Non-Hodgkin lymphoma (NHL) is the seventh most common diagnosed malignancy in the world. 5 Chronic lymphocytic leukemia (CLL) is a member of the NHL family and represents a large proportion of all leukemias; it is classified as a lowgrade lymphoproliferative malignancy characterized by a clonal expansion of B-cells.…”

Section: Introductionmentioning

confidence: 99%

CutaneousT‐cell lymphoma in patients with chronic lymphocytic leukemia: clinical characteristics, temporal relationships, and survival data in a series of 14 patients atMayoClinic

2013

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Section: Introductionmentioning

confidence: 99%

CutaneousT‐cell lymphoma in patients with chronic lymphocytic leukemia: clinical characteristics, temporal relationships, and survival data in a series of 14 patients atMayoClinic

2013

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“…Pruritis was the principal functional sign, reported by the majority of the patients. In the literature, DH is classically accompanied by intense pruritis [1,4,7,13,14].…”

Section: Clinical Aspectsmentioning

confidence: 99%

“…Histology makes little contribution to the diagnosis. The reference diagnostic test for DH is direct immunofluorescence (DIF) [1,14], which is unavailable in our context.…”

Section: Paraclinical Aspectsmentioning

confidence: 99%

“…A gluten-free diet was initiated in all patients. It is indispensable for the management of DH [1,14], yet is difficult to follow. Treatment with dapsone (2 mg/kg/day) was offered to the fourteen patients.…”

Section: Treatmentmentioning

confidence: 99%

“…

Dermatitis herpetiformis (DH) is a rare, recurrent auto-immune bullous dermatosis classically associated with gluten enteropathy. It predominantly affects Caucasians, with a sex ratio of 1.8 [1]. The prevalence is higher in northern Europe, ranging from 11 to 66 cases per 100,000 inhabitants [2,3].

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confidence: 99%

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Epidemiological, clinical and therapeutic aspects of dermatitis herpetiformis at Yalgado Ouédraogo University Hospital Centre, Burkina Faso

Ouédraogo,

Djounitanan,

Ouédraogo

et al. 2023

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Background: Dermatitis herpetiformis is a rare autoimmune bullous dermatosis that predominantly affects Caucasians, adults or children, with a sex ratio of 1.8. Materials and Methods: The aim of this study was to document the clinical and epidemiological profiles of dermatitis herpetiformis and to detail its treatment in a hospital setting in order to increase our knowledge about this disease in our context and so to improve its management. We conducted a retrospective, cross-sectional study of the records of all patients seen in consultation or hospitalized at the dermatology department of Yalgado Ouédraogo University Hospital Centre, Ouagadougou, a public hospital in Burkina Faso, from January 2016 to December 2020. Results: We collected 14 cases (0.12%) of dermatitis herpetiformis among 11,456 patients seen. The mean age was 8 years (ranging from 4 to 27 years). The sex ratio was 1.33. The majority of the patients were schoolchildren living in rural areas (8 cases). The duration of the disease ranged from five days to one year (mean duration: 59.35 days). Eight patients had a history of digestive problems such as abdominal pain and diarrhea. Pruritis was the principal functional sign. In all patients, the lesions were polymorphous: disseminated vesicular bullae, papules, erosive, and excoriated lesions, sometimes forming clusters. Mucosal involvement was rare (3 cases). A gluten-free diet and dapsone 2 mg/kg/day were proposed to all patients and resulted in the improvement of the lesions. Conclusion: Our study confirmed that dermatitis herpetiformis is rare in our context. It is more frequent in young children and predominantly affects boys. It is intensely pruritic, and generalized polymorphous lesions were present in all our patients. Treatment is essentially based on a gluten-free diet and dapsone, which is a therapeutic test in the absence of supplementary investigations to establish a definitive diagnosis. Key words: Dermatitis Herpetiformis; Clinical Medicine; Dapsone; Gluten Intolerance

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