Atypical Presentations of Pediatric-Acquired Thrombotic Thrombocytopenic Purpura
Amit Ziv,
Rima Dardik,
Joanne Yacobovich
et al.
Abstract:Background:
Immune thrombotic thrombocytopenic purpura (iTTP) in children is a rare, severe thrombotic microangiopathy. This condition is characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and organ ischemia due to reduced activity of the von Willebrand factor-cleaving protease ADAMTS13.
Methods:
A retrospective case series evaluating data collected from the medical files of 4 children diagnosed with iTTP.
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