Atypical presentation of tuberculosis

Deshpande, Ashwini; Gupta, Prashant; Reddy, A Vikram Simha; Reddy, G V Ramachandra

doi:10.4103/jomfp.jomfp_56_20

Cited by 6 publications

(6 citation statements)

References 3 publications

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“…This highlights the importance of considering TB as a differential diagnosis even in the absence of typical symptoms. 3,5,6,15 The rapid onset and progression of symptoms, in this case, was also unusual for TB. Typically, TB presents with a more insidious onset, with symptoms developing gradually over several weeks to months.…”

Section: Discussionmentioning

confidence: 53%

“…1,2 TB can present with classical symptoms such as fever, cough, and weight loss, but it can also have atypical presentations with a varied range of symptoms, making it challenging to diagnose. [3][4][5][6] Atypical presentations of TB are those that do not fit the typical profile of the disease. While classical symptoms such as cough, fever, and weight loss are commonly associated with TB, atypical presentations can manifest in various ways, including extrapulmonary TB, which can involve different organs, such as the bones, lymph nodes, and abdomen, among others.…”

mentioning

confidence: 99%

“…Additionally, patients with comorbidities such as HIV/AIDS or diabetes mellitus may experience atypical presentations of TB due to impaired immune function. 3,5,6,8 TB treatment consists of a combination of antibiotics, typically for a period of six to nine months. The first-line drugs used to treat TB, as seen in this case, include isoniazid, rifampicin, ethambutol, and pyrazinamide.…”

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confidence: 99%

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Atypical presentation of tuberculosis: a case report highlighting the challenges of diagnosis and management

et al. 2023

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Tuberculosis (TB) remains a significant public health issue worldwide and can present with atypical symptoms, making it difficult to diagnose. Atypical TB symptoms include non-specific symptoms and extrapulmonary TB, and patients with comorbidities may present with atypical TB due to impaired immune function. TB treatment includes antibiotics, which can cause hepatotoxicity, and require close monitoring for signs of liver injury. A 32-year-old female with intellectual developmental disorders was admitted to the hospital with suspected pneumonia and acute respiratory viral infection. Despite initial treatment with antibiotics, her oxygen saturation decreased, and she developed recurrent pneumothorax on the right side and neutrophilic pleuritis. Computed tomography (CT) scans showed increasing infiltrative changes, and bronchoalveolar lavage eventually revealed Mycobacterium tuberculosis DNA, leading to the diagnosis of tuberculosis pneumonia with pleurisy. This case report highlights the challenges of diagnosing TB and the importance of maintaining a high index of suspicion for TB in patients who do not fit the typical profile of the disease. The case also emphasizes the potential for drug-induced liver damage with TB treatment and the need for close monitoring. Early diagnosis and appropriate management are crucial to prevent further complications and improve outcomes in patients with TB.

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Section: Discussionmentioning

confidence: 53%

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confidence: 99%

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confidence: 99%

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Atypical presentation of tuberculosis: a case report highlighting the challenges of diagnosis and management

et al. 2023

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“…In primary disease, the mouth is the initial site of infection without any focus of systemic tuberculosis. In secondary disease, CT develops secondary to internal organ tuberculosis as a result of autoinoculation [31,32].…”

Section: Macro Cheilitis Tuberculosismentioning

confidence: 99%

Dermoscopy of Cheilitis: A Comprehensive Review of Principal Findings

Imane,

Sara,

Sara

et al. 2023

J Dermatol Res Ther

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Cheilitis, an inflammatory condition affecting the lips, presents with various etiologies and clinical manifestations. Early and accurate diagnosis of cheilitis is essential for appropriate treatment and management. Dermoscopy has emerged as a valuable diagnostic tool in dermatology, allowing for non-invasive visualization of skin structures. This review article aims to provide an in-depth understanding of dermoscopic findings in the context of cheilitis, including the identification of specific features associated with different types of cheilitis and the potential role of dermoscopy in guiding treatment decisions.

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“…В орофациальной области микобактерии туберкулеза (МБТ) могут поражать лимфатические узлы головы, лица и шеи, миндалины, слюнные железы, челюсти, твердое и мягкое небо, жевательные мышцы, слизистые оболочки щек, десен, языка и язычка [1][2][3][4][5][6]. Лидирующую позицию среди перечисленных локализаций занимает ротовая полость, согласно данным различных исследований, оральный туберкулез составляет от 0,05 до 5% среди всех зарегистрированных случаев [7][8][9][10][11]. О поражении полости рта сообщалось очень давно: впервые случай туберкулеза языка описан в 1761 году [12], позже -в 1888 году [13], в 1893 году сообщалось о случае туберкулеза околоушной железы [14].…”

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Tuberculous Glossitis - A Rare Extrapulmonary Localization

Kukurika

2021

Juvenis scientia

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Tuberculous glossitis is very rare, even in countries with a high tuberculosis burden. The tongue is the most frequent lesion in the structure of oral forms, the frequency of which does not exceed 0.1%. Allocate sputtogenic and hematogenous pathways of infection. The protective function of saliva, due to enzymes and antibodies in its composition, the pH of the oral cavity, the peculiarities of the blood supply, the presence of variable saprophytic microflora, a small number of lymphoid follicles, complicates the inoculation of mycobacterium tuberculosis. However, defects of the mucous membrane due to trauma, invasive interventions and chronic nonspecific inflammation in the oral cavity create favorable conditions for the vital activity of the pathogen. Analyzed 38 clinical cases of tuberculous glossitis from foreign practice, presented their brief description. The issue of timely detection and differential diagnosis of tuberculous glossitis is relevant in the practice of doctors of various profiles. Any lesion of the tongue should be carefully investigated, diagnostics should include laboratory, histological and radiation methods.

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Atypical presentation of tuberculosis

Cited by 6 publications

References 3 publications

Atypical presentation of tuberculosis: a case report highlighting the challenges of diagnosis and management

Atypical presentation of tuberculosis: a case report highlighting the challenges of diagnosis and management

Dermoscopy of Cheilitis: A Comprehensive Review of Principal Findings

Tuberculous Glossitis - A Rare Extrapulmonary Localization

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