Atypical presentation of coeliac disease

Furse, R M; Mee, A S

doi:10.1136/bmj.330.7494.773

Cited by 27 publications

(22 citation statements)

References 7 publications

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“…As in our case, many patients of celiac disease starting GFD realized that many of their gastrointestinal problems which they had perceived as almost normal, disappeared [21]. Since half of the cases with Lane Hamilton syndrome in literature had no bowel involvement, we suggest that all patients of IPH should be investigated for CD.…”

Section: Discussionmentioning

confidence: 52%

Hemoptysis in patients of celiac disease with disproportionately severe anemia: tip of the iceberg?

Singhal

Janmeja

Sodhi

et al. 2013

Multidiscip Respir Med

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Idiopathic Pulmonary Hemosiderosis (IPH) is characterized by the triad of iron deficiency anemia, pulmonary infiltrates and haemoptysis with no recognizable cause. Since the first description of its association with Celiac Disease (CD) by Lane and Hamilton in 1971, only a few isolated cases have been reported in literature. Although it has been considered an uncommon association of two disease entities, recent reports indicate that prevalence of celiac disease is as high as one percent. Further, individually both celiac disease and IPH are known to present as refractory anemia only. We are reporting a young adult with Lane Hamilton Syndrome, who realized that he was having significant gastrointestinal complaints only when they disappeared on gluten free diet (GFD). This case report reiterates the fact that celiac disease should be considered in all patients of IPH because of the therapeutic implications. Further on review of literature, we believe that covert hemoptysis may be responsible for disproportionately severe anemia in patients of celiac disease. Thus, prevalence of this association may be more than currently believed. Further research in this regard may improve our understanding of pathogenesis of celiac disease.

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Section: Discussionmentioning

confidence: 52%

Hemoptysis in patients of celiac disease with disproportionately severe anemia: tip of the iceberg?

Singhal

Janmeja

Sodhi

et al. 2013

Multidiscip Respir Med

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“…A minority of adults show signs of malabsorption, and many present in other ways, for example with symptoms suggesting gastro‐oesophageal reflux 3. Obesity is well recognized in adults 3,4, but is rarely reported as a presenting feature in children. One published case concerned a 5‐y‐old girl with short stature and recurrent abdominal pain 5.…”

Section: Discussionmentioning

confidence: 99%

A boy with coeliac disease and obesity

Oso

Fraser

2006

Acta Paediatrica

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Aim: To report the case of a 14‐y‐old boy with coeliac disease and obesity. Methods and results: A 14‐y‐old boy presented with episodic diarrhoea associated with eating spaghetti. His body mass index (BMI) at presentation was 37.2 kg/m2 (>99.9th centile). Both antigliadin and anti‐endomysial antibodies were positive, and coeliac disease was diagnosed by jejunal biopsy. His diarrhoea ceased and the gliadin and endomysial antibodies disappeared after starting gluten‐free diet. At 17 y, his BMI increased to 42.7 kg/m2 despite dietary support. Conclusion: Obesity in a child does not exclude the diagnosis of coeliac disease, especially if presenting with suggestive symptoms.

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“…Furse and Mee (2005) [7] describe atypical presentations of CD in four obese women with a BMI over 40 kg/m 2 . Semenaro (1986) [8] postulates that obese CD patients are probably able to compensate for proximal malabsorption by using intact absorptive mechanisms more distally.…”

Section: Discussionmentioning

confidence: 99%