2021
DOI: 10.29271/jcpsp.2021.06.719
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Atypical Polypoid Adenomyoma (APAM)

Abstract: Atypical polypoid adenomyoma (APAM) is a rare polypoidal benign tumor of uterus, which usually presents with irregular vaginal bleeding in women of reproductive age. It has the potential of malignant transformation but does not metastasise. It may coexist with endometrial hyperplasia and adenocarcinoma; and so, is usually misdiagnosed. It is composed of atypical endometrial glands along with bundles of smooth muscle fibres. It has a high incidence of recurrence. We describe a case of APAM, which was managed at… Show more

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Cited by 3 publications
(3 citation statements)
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“…Based on publication data, atypical polypoid adenomyoma (APA) is an endometrial tumor with low malignant potential and low incidence rate, which generally occurs in patients of reproductive age. Being considered as an indicator or precursor for endometrial endometrioid adenocarcinoma or coexisted with endometrioid adenocarcinoma [ 6 , 7 , 8 ], it should be treated from the beginning as a potential-aggressive tumor in order to avoid delays in therapy. Moreover, it is mandatory to inform the patient about all these risks.…”
Section: Discussionmentioning
confidence: 99%
“…Based on publication data, atypical polypoid adenomyoma (APA) is an endometrial tumor with low malignant potential and low incidence rate, which generally occurs in patients of reproductive age. Being considered as an indicator or precursor for endometrial endometrioid adenocarcinoma or coexisted with endometrioid adenocarcinoma [ 6 , 7 , 8 ], it should be treated from the beginning as a potential-aggressive tumor in order to avoid delays in therapy. Moreover, it is mandatory to inform the patient about all these risks.…”
Section: Discussionmentioning
confidence: 99%
“…Protrusions are often present as polyps and submucosal myomas; however, they might also be present in atypical and malignant diseases such as atypical polypoid adenomyoma and some EC. 6,7 Desquamation is when a small white mass, assumed to be necrotic tissue flaking from the endometrium, floats in the uterine cavity and appears as a snowstorm. This phenomenon has been previously reported to be a characteristic observed, for example, in patients with abnormal uterine bleeding and irregular endometrium or malignant possibility.…”
Section: Hysteroscopymentioning
confidence: 99%
“…Atypical vessels include those with meandering, expansion, inconsistent diameter, and disruption, frequently mentioned as features representing endometrial malignancy. 4,6,10 A white/ yellow lesion indicates focal necrosis or microcalcifications on the endometrial surface. 5 An experienced consultant, blinded to the pathology results, retrospectively judged these five features as positive or negative using hysteroscopy videos.…”
Section: Hysteroscopymentioning
confidence: 99%