Atypical pityriasis rosea and Hodgkin's disease†

García‐F‐Villalta, MJ; Hernández‐Núñez, A.; Córdoba, Susana; Fernández‐Herrera, Jesús; García‐Diez, Amaro

doi:10.1111/j.1468-3083.2004.00610.x

Cited by 10 publications

(5 citation statements)

References 7 publications

(24 reference statements)

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“…In addition, HHV 6 has been found in the oligodendrocytes and serum of patients with multiple sclerosis and not in control subjects. 79 PR-like eruptions have been associated with several neoplasms (gastric, bronchogenic), 37 T-cell lymphomas, 36 Hodgkin disease, 41 and bone-marrow transplantation. 38 The rashes are PR-like even from a histopathologic point of view, and are sometimes atypical both clinically and histologically.…”

Section: Associationsmentioning

confidence: 99%

See 1 more Smart Citation

Pityriasis rosea: An update with a critical appraisal of its possible herpesviral etiology

Drago

Broccolo

Rebora

2009

Journal of the American Academy of Dermatology

170

163

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Section: Associationsmentioning

confidence: 99%

“…Although rare, cases of PR have been described in patients after bone-marrow transplantation, [36][37][38] in human immunodeficiency infection 39,40 and in other conditions, such as hematologic disorders 36,41,42 or treatment with immunomodulating drugs, 43 well known to induce a state of altered immunity.…”

Section: Pr In Immunocompromised Patientsmentioning

confidence: 99%

Pityriasis rosea: An update with a critical appraisal of its possible herpesviral etiology

Drago

Broccolo

Rebora

2009

Journal of the American Academy of Dermatology

170

163

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“…To our best knowledge, there exists only two reported patients with Hodgkin lymphoma and PR (15,16). The rashes were atypical for both patients.…”

Section: Discussionmentioning

confidence: 99%

“…As aforementioned, PR might be associated with underlying Hodgkin lymphoma, (15,16) and this article depicted PR associated with NHL. Cutaneous malig- © C I C E d i z i o n i I n t e r n a z i o n a l i nancies such as cutaneous T-cell lymphoma (18), basal cell carcinoma (19), squamous cell carcinoma (19), mycosis fungoides (20), and haematological malignancies such as acute myeloid leukaemia (21) can present as rashes akin to PR.…”

Section: Malignanciesmentioning

confidence: 99%

The first reported patient with non-Hodgkin lymphoma presenting as pityriasis rosea

Chuh¹

2015

cderm

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SummaryBackground. Owing to the spontaneous remission with no complication being the rule, pityriasis rosea (PR) has been termed Doctor's Delight. Only two patients have been reported to have Hodgkin lymphoma and atypical PR concomitantly. There exists no report on the association of PR and non-Hodgkin lymphoma. Case report. We present a 62-year-old male patient with fever and coryzal symptoms, followed by a herald patch at the right inferior quadrant of his anterior abdominal wall. One week later, generalised skin lesions erupted on his trunk and proximal aspects of his four limbs. We saw him 12 days after onset of the primary patch. Examination revealed clinical features entirely compatible with classical PR. Systemic examination revealed enlarged and firm inguinal lymph nodes bilaterally. Spontaneous rash resolution occurred two weeks later. As the inguinal lymph nodes were still enlarging over time, we referred him to a physician. Lymph node biopsy revealed non-Hodgkin lymphoma. Discussion. This is the first reported patient with non-Hodgkin lymphoma presenting as classical PR. PR in the elderlies, pregnant women, people with autoimmune diseases or tendencies, people after organ transplantation, and immunocompromised people might be at a higher risk of serious underlying diseases or severe complications, and are important exceptions for this Doctor's Delight.

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“…3 Non-specific cutaneous manifestations are a diverse group and have been described in the literature in case reports and at least one study. 2,5,6 Our case report represents a pityriasis rosea-like eruption ("atypical" pityriasis rosea) which may be a clue to the underlying disease process.…”

Section: Introductionmentioning

confidence: 99%

Pityriasis rosea-like cutaneous eruption as the presenting symptom of Hodgkin lymphoma. Case report and review of the literature.

Vrotsos

Dosal

Zaiac

et al. 2015

J Dermatol Case Rep

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Background: Cutaneous involvement by Hodgkin lymphoma is extremely rare and usually follows extensive involvement of the lymph nodes. Cutaneous manifestations of Hodgkin lymphoma may be divided into specific and non-specific. Generalized pruritus is one of the most common non-specific presentations of Hodgkin lymphoma as is cutaneous granulomas. Such signs and symptoms should prompt thorough physical exam, including evaluation of lymph nodes, especially in a young patient. Main observation: We report a case of a 22-year-old man who presented with night sweats, weight loss, dry cough, and generalized maculopapular eruption that started with a large patch in the center of the chest and spread to the extremities. Biopsy of the rash revealed pityriasis rosea-like findings. A computerized tomography scan of the chest revealed a mediastinal mass. Biopsy of the mediastinal mass revealed Reed-Sternberg cells in a fibrotic background, diagnostic of Hodgkin lymphoma, nodular sclerosis type. Conclusion:In conclusion, the presentation of Hodgkin lymphoma as a pityriasis rosea-like cutaneous eruption is rare and clinicians should be aware of this presentation. In this paper we review the non-specific cutaneous manifestations of Hodgkin lymphoma in an effort to raise awareness of the diversity of early cutaneous signs of Hodgkin lymphoma. (J Dermatol Case Rep. 2015; 9(3): 81-84)

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Atypical pityriasis rosea and Hodgkin's disease†

Cited by 10 publications

References 7 publications

Pityriasis rosea: An update with a critical appraisal of its possible herpesviral etiology

Pityriasis rosea: An update with a critical appraisal of its possible herpesviral etiology

The first reported patient with non-Hodgkin lymphoma presenting as pityriasis rosea

Pityriasis rosea-like cutaneous eruption as the presenting symptom of Hodgkin lymphoma. Case report and review of the literature.

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