Atypical, Extremely Rapid Growth of Pediatric Orbital Neurilemmoma

Abstract

Solitary orbital neurilemmoma—a benign tumor of Schwann cells in a peripheral nerve-sheath—are typically very slow growing and present in middle age; in the absence of neurofibromatosis, they are almost never seen in childhood. We describe the clinical presentation, imaging, pathology, and management of this tumor in a 12 years old—the tumor growing extremely rapidly over 5 months and without any evidence of cystic degeneration, hemorrhage, or sarcomatous features. The possibility of tumor growth having been accelerated by prior biopsy is discussed.

Pediatric dumbbell-shaped orbital schwannoma with extension to the cranial cavity: A case report and literature review

“…Schwannoma arises from Schwann cells and are known to originate from the sensory branches of the ophthalmic division of the trigeminal nerve in an orbit ( 3 ). Schwannomas occur in middle age and are usually rare in children with the absence of neurofibromatosis ( 4 ). We discussed a 12-year-old boy who had a dumbbell-shaped schwannoma, and most of the lesions were found in the left orbit with a small portion in the left cavernous sinus.…”

Orbital schwannoma with hyposmia as the only presentation: Case report and a literature review on differential diagnosis

“…In some cases, orbital schwannoma with a cyst formation may grow rapidly. 3 Preoperative diagnosis of orbital schwannomas is still difficult, which depends on multiple imaging modalities including ultrasonography, computed tomography (CT), and magnetic resonance imaging (MRI). Due to the varied appearances of lesions on various imaging modalities, imaging results should be comprehensively considered for differential diagnosis.…”