“…Although pharmacologic treatments such as nonsteroidal anti-inflammatory medications can be used as analgesics in combination with anticonvulsants, calcium channel blockers, or tricyclic antidepressants with anticholinergic effects, the efficacy rates of these treatments are low. 84 A more recent treatment option includes intraparotid botulism toxin injection, although the long-term efficacy of this treatment option remains ill defined. 85 Similar to HS, FBS can be transient and resolve over time, but it is often very disabling and persistent, as evidenced by the cases evaluated in our review.…”