Atypical Cavernous Sinus Thrombosis: A Diagnosis Challenge and Dilemma

Matthew, Tong Jong Haw; Hussein, Adil

doi:10.7759/cureus.3685

Cited by 13 publications

(15 citation statements)

References 10 publications

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“…[6,7] A non-contrast CT scan of the head may show several abnormalities such as vascular edema, protrusion of the lateral margin of the cavernous sinus, exophthalmos, and the presence of sphenoid or ethmoid sinusitis, or mass lesions near the sphenoid or pituitary gland. [4] There were signs of inflammation in an increase in leukocytes, CRP, ESR, and D-dimer on laboratory examination. On examination of pus culture, bacterial growth was found.…”

Section: Discussionmentioning

confidence: 99%

“…Cavernous sinus thrombosis is a complication of infection around the face or paranasal sinuses with a high morbidity and mortality rate. [4] The rare incidence and overlapping complaints of eye disease are generally at risk of delaying diagnosis and resulting in increased morbidity. [5] Cavernous sinus thrombosis is generally caused by septic infection, including infections around the face, especially within the "triangle of the face," including abscesses or cellulitis, dental sinusitis, otitis media, and mastoiditis.…”

Section: Discussionmentioning

confidence: 99%

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Cavernous Sinus Thrombosis as Complications of Cellulitis Orbital: Case Report

Goller

Tini

2021

Int J Res Rev

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Background: Cavernous sinus thrombosis is a complication of infection around the face or paranasal sinuses with high morbidity and mortality rates. Cavernous sinus thrombosis is generally caused by septic infection, such as orbital cellulitis. Case Illustrations: A 35-year-old male who came to the neurology polyclinic complained of swelling in the left eyelid, red, watery eyes, blurred vision, difficulty opening the left eye, and the movement of the left eyeball felt normal. The patient had a history of left orbital cellulitis. Laboratory investigations showed an increase in inflammatory markers. The CT scan with contrast showed a hyperdense lesion in the left orbit, suggesting orbital cellulitis. The patient was diagnosed with a cavernous sinus thrombosis due to orbital cellulitis. He was treated with an antibiotic, anticoagulant, and corticosteroid. Three months after treatment, the visual complaints improved, the headache decreased drastically, and we did not find any extraocular muscles weakness. Conclusions: The administration of antibiotics and anticoagulant therapy in patients with cavernous sinus thrombosis has been proven clinically. The use of corticosteroids has not been proven but is strongly suspected to reduce edema caused by compression of the cavernous sinus. Keywords: Cavernous sinus thrombosis, orbital cellulitis. infections.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cavernous Sinus Thrombosis as Complications of Cellulitis Orbital: Case Report

Goller

Tini

2021

Int J Res Rev

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“…Despite the reports on the occurrence of fungal sphenoid sinusitis leading to cavernous sinus thrombophlebitis, a wide literature search did not yield any publication on mucormycosis in an immunocompetent patient without diabetes. The anatomical importance of the sphenoid sinus is due to its proximity and location between both cavernous sinuses [ 6 ]. The proposed mechanism involves hematogenous spread causing the fungi to adhere to the endothelium of neighboring blood vessels, resulting in thrombus formation.…”

Section: Discussionmentioning

confidence: 99%

Isolated Fungal Sphenoid Sinusitis With Cavernous Sinus Thrombophlebitis: A Case Report

Nunez¹,

Tiongson²

2022

Cureus

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Cavernous sinus thrombophlebitis is a rare, potentially life-threatening, condition that is most often caused by gram-negative bacteria and, to a lesser extent, fungi. Mucor is an opportunistic fungus that frequently affects patients with a weak immune system. We describe a case of an adult female without diabetes who developed Mucor sphenoid sinusitis causing cavernous sinus thrombophlebitis. The patient presented with headache, diplopia, and right lateral rectus palsy. Cranial magnetic resonance imaging (MRI) showed abnormal prominent enhancement involving the cavernous sinuses associated with interspersed internal non-enhancing components indicating bilateral cavernous sinus thrombophlebitis and exuberant inspissated secretions within the left sphenoid sinus. After administering enoxaparin and intravenous antibiotics, the patient underwent endoscopic transnasal sphenoidotomy with nasal polypectomy. Culture results showed growth of mucor, for which the patient received itraconazole. Thereafter, complete resolution of headache, diplopia, and right lateral rectus palsy was observed. On follow-up, no residual neurologic deficits were noted. The repeat cranial MRI showed no abnormality involving the cavernous sinuses, with no evidence of cavernous sinus thrombophlebitis and normal paranasal sinuses. While a few case reports have been available on cavernous sinus thrombophlebitis caused by fungal sphenoid sinusitis with Mucor as the primary organism, none have involved immunocompetent individuals.

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“…Esse dado é relativamente preocupante, pois as infecções odontogênicas complexas são apontadas como um problema relevante de saúde pública 14 . Nos estágios onde essa infecção atinge órgãos importantes, como o coração e o cérebro, o paciente pode ter um quadro de envolvimento das vias aérea e trombose do seio caverno, podendo causar até a morte 15 .…”

Section: Discussionunclassified

Percepção de universitários de uma instituição de ensino superior do Alto Sertão da Paraíba - Brasil a respeito de agravos sistêmicos frente a infecções odontogênicas

Gomes¹,

Oliveira²,

Sousa³

et al. 2021

Arch Health Invest

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As infecções odontogênicas são processos causados por cárie dentária, infecções endodônticas, pericoronarite e doenças periodontais. Em casos evoluídos, pode ocorrer a disseminação para regiões importantes do corpo. O objetivo do presente estudo foi avaliar a percepção de universitários de uma Instituição de Ensino Superior (IES) do alto sertão paraibano sobre a evolução das infecções odontogênicas. O trabalho em questão refere-se a um estudo transversal, de natureza descritiva e quantitativa, o qual foi realizado com os universitários matriculados na Faculdade Santa Maria, de todos os cursos de graduação (exceto Odontologia) e de todos os períodos. Foi realizado por meio de um questionário on-line estruturado, aplicado através da plataforma Google Forms e composto de três etapas. Foram entrevistados 143 universitários de ambos os sexos, entre as idades de 18 a 54 anos, sendo a maior parte mulheres (83,9%) e a idade mais prevalente compreende os indivíduos entre os 18 a 30 anos (85%). Em relação ao conhecimento sobre cárie dentária, 97,2% responderam que conheciam a doença. Quando indagados sobre ao entendimento de como evitar a cárie e a gengivite, 77,6% dos alunos responderam que sabiam métodos para evitar o surgimento das doenças. Mais da metade dos alunos (55,9%) responderam que concordavam totalmente que a cárie dentária e um canal não tratado poderiam ocasionar a formação de conteúdo purulento. Os resultados sugerem que os alunos da Faculdade Santa Maria possuem um bom conhecimento relacionado a infecções odontogênicas e seus agravos. Porém, esse conhecimento é limitado, mostrando assim que o mesmo deve ser aprofundado.

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Atypical Cavernous Sinus Thrombosis: A Diagnosis Challenge and Dilemma

Cited by 13 publications

References 10 publications

Cavernous Sinus Thrombosis as Complications of Cellulitis Orbital: Case Report

Cavernous Sinus Thrombosis as Complications of Cellulitis Orbital: Case Report

Isolated Fungal Sphenoid Sinusitis With Cavernous Sinus Thrombophlebitis: A Case Report

Percepção de universitários de uma instituição de ensino superior do Alto Sertão da Paraíba - Brasil a respeito de agravos sistêmicos frente a infecções odontogênicas

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