Atypical Case of COVID-19 Associated Kawasaki Disease in an Eight-Year-Old Pakistani Boy

Abstract

People of all age groups have been affected worldwide during the coronavirus disease 2019 (COVID-19) pandemic. While the global efforts of researchers, clinicians, and scientists are underway, cases involving multiple systems with a wide range of presentations are on the horizon. As health organizations have started warnings about unusual manifestations of a Kawasaki disease (KD)-like inflammatory syndrome associated with COVID-19, some pediatric cardiologists noted that even classic cases are likely going undercounted. Here we report a case of a previously healthy eight-year-old Pakistani boy who presented with a four-day history of low-grade fever. The patient was admitted and diagnosed with COVID-19-associated atypical KD in the setting of fever for more than five days, maculopapular eruptions, and mild conjunctivitis. He screened positive for COVID-19 with an immunoglobulin G titer of 2.1 plus ruling out other childhood illnesses. He was managed with intravenous immunoglobulins and aspirin with gradual resolution of symptoms. His initial echocardiogram was unremarkable. He was discharged home on day six with a follow-up at two weeks.

A novel case of lupus nephritis and mixed connective tissue disorder in a COVID-19 patient

“…COVID-19 causes a broad spectrum of clinical symptoms that impact various body systems, often appearing with respiratory signs and symptoms, such as flu-like illness exacerbated by acute respiratory distress syndrome (ARDS) and lung failure [ 4 , 5 ]. Additional symptoms and risks include severe metabolic syndrome, acute renal injury, neurological diseases, cardiovascular and thromboembolic events such as encephalopathy, seizures, and stroke [ [6] , [7] , [8] , [9] , [10] ]. A possible relationship between COVID-19 and autoimmune diseases such as SLE has also been recently documented in many case reports within the literature [ [11] , [12] , [13] ].…”

A Flare of Systemic Lupus Erythematosus Disease After COVID-19 Infection: A Case of Lupus Cerebritis

“…COVID-19 generally presents with signs and symptoms of the respiratory system, including flu-like illness complicated by acute respiratory distress syndrome (ARDS) and lung failure [2]. Other manifestations and complications include severe metabolic syndrome, acute kidney injury, neurological syndromes, cardiovascular and thromboembolic events such as encephalopathy, seizures, and stroke [3][4][5][6][7]. A possible association between COVID-19 and autoimmune disease has also been reported in many case reports [8].…”

Shock por enfermedad de Kawasaki post COVID-19: a propósito de un caso

“…Sumado a esto, recientemente se han descrito diversos cuadros clínicos e incluso de índole neurológico (Paybast et al, 2020). Particularmente en la población pediátrica se ha asociado la aparición de la enfermedad de Kawasaki (EK) a la COVID-19 (Khan et al, 2020).…”