2015
DOI: 10.4322/acr.2015.021
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Atypical behavioral and psychiatric symptoms: neurosyphilis should always be considered

Abstract: Syphilis still remains a major health concern worldwide because of the possibility of serious medical and psychological consequences, long-term disability, and death. Neurosyphilis (NS) may occur at any stage of infection. Its clinical presentation has been changing over recent years including­ psychiatric and neurocognitive symptoms. Several recent studies have described cases with these symptoms as the principal signs of NS. We present the case of neurosyphilis with a psychiatric presentation characterized b… Show more

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Cited by 17 publications
(17 citation statements)
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References 15 publications
(21 reference statements)
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“…The case also il lus trates that spe cific an ti bacte rial treat ment leads the pa tients to re mis sion very quickly and ef fec tively [8]. Crozatti et al (2015) re ported a case with a dif fer ent clin i cal course -the man i fes ta tion of the dis ease was of a de pres sive na ture with sui cidal thoughts and cog ni tive dis tur bances. What is also in ter est ing, is that dur ing the course of treat ment, some psy chotic symp toms, par tic u larly para noid ideation and persecutory de lu sions ap peared, which would also sup port the idea of the ex treme un pre dict abil ity of neurosyphilis.…”
Section: Discussionmentioning
confidence: 83%
“…The case also il lus trates that spe cific an ti bacte rial treat ment leads the pa tients to re mis sion very quickly and ef fec tively [8]. Crozatti et al (2015) re ported a case with a dif fer ent clin i cal course -the man i fes ta tion of the dis ease was of a de pres sive na ture with sui cidal thoughts and cog ni tive dis tur bances. What is also in ter est ing, is that dur ing the course of treat ment, some psy chotic symp toms, par tic u larly para noid ideation and persecutory de lu sions ap peared, which would also sup port the idea of the ex treme un pre dict abil ity of neurosyphilis.…”
Section: Discussionmentioning
confidence: 83%
“…Th ere are many case reports that underline the fact that appropriate treatment may be delayed due to nonspecifi c psychiatric symptoms. For instance, Costiniuk and MacPherson eported 3 patients who presented with sleep disturbances, psychosis, hyperactivity, seizures, cognitive impairment, lower-limb weakness and dysarthria 5,6 .…”
Section: Resultsmentioning
confidence: 99%
“…; Crozatti et al. ). More recent studies have looked at the effect of enteric bacteria on mental health.…”
Section: The Microbiome‐gut‐brain Axis and Mental Diseasementioning
confidence: 98%