Attractive study of the antimicrobial, antiviral, and cytotoxic activity of novel synthesized silver chromite nanocomposites

Sayed, Mohsen A.; El-Rahman, Tahany M.A. Abd; Abdelsalam, H. K.; Ali, Ahmed M.; Hamdy, M.; Badr, Yara A.; Rahman, Nada H. Abd El-; El-Latif, Sabah M. Abd; Mostafa, Sara H.; Mohamed, Sondos S.; Ali, Ziad M.; El-Bassuony, Asmaa A. H.

doi:10.1186/s13065-022-00832-y

Cited by 15 publications

(15 citation statements)

References 58 publications

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“…However, the surface spins anisotropy in chromite NPs are responsible to the lowest value of M s [42]. According to Sayed et al [117], the high M s provided notable antibacterial performance. Furthermore, the narrow M-H loops of the prepared samples provide small M r values, which positively affect biomedical applications [118].…”

Section: Vsm Measurementsmentioning

confidence: 99%

Fabrication, characterization, and antibacterial activity of ferrite, chromite, and aluminate nanoparticles

El Hajjar,

Bitar,

Zahr

et al. 2024

Mater. Res. Express

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Zn0.33Co0.33Mg0.33X2O4 nanoparticles (NPs), where X = Fe, Cr, Al and denoted by F, C, and A, were prepared by the co-precipitation method. X-ray diffraction patterns validated the formation of NPs with cubic spinel structure with the detection of small amounts of impurities in samples C (Cr2O3) and A (MgO). Transmission electron micrographs showed a nearly spherical shape for samples F and A. However, sample C revealed cubic and nearly spherical shapes. Energy-dispersive x-ray analysis ensured the presence of chemical constituents in all samples. The vibrational modes of NPs were confirmed with Fourier transform infrared spectroscopy. The direct bandgap energy values, calculated using ultraviolet-visible spectroscopy, were in the range of 2.355 and 2.967 eV for F, C, and A samples. X-ray photoelectron spectroscopy analysis confirmed the compositions as well as the valence states of all elements. Magnetic hysteresis (M–H) loops revealed a soft ferromagnetic behavior. Sample F exhibited a higher saturation magnetization, remanent magnetization, magnetic moment, and magnetic anisotropy compared to those of samples C and A. The antibacterial activity of the tested samples against four bacteria (Staphylococcus aureus, Stenotrophomonas maltophilia, Escherichia coli, and Enterococcus faecium) was determined using the broth microdilution assay, minimum bactericidal concentration (MBC), and time-kill test. The prepared NPs exhibited varying antibacterial activity due to multiple factors. These results highlighted the potential utility of the ternary ferrite, chromite, and aluminate NPs in the treatment of microbial infections, particularly multidrug-resistant bacteria.

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Section: Vsm Measurementsmentioning

confidence: 99%

Fabrication, characterization, and antibacterial activity of ferrite, chromite, and aluminate nanoparticles

El Hajjar,

Bitar,

Zahr

et al. 2024

Mater. Res. Express

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“…Other studies have evaluated the antifungal and cytotoxic activities of different silver chromite (Ag-CrNPs) nanocomposites [ 107 ]. Nanocomposites are hybrid materials in which at least one component has nanometric dimensions [ 108 ].…”

Section: Metal Nanoparticlesmentioning

confidence: 99%

Metal Nanoparticles to Combat Candida albicans Infections: An Update

et al. 2023

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Candidiasis is an opportunistic mycosis with high annual incidence worldwide. In these infections, Candida albicans is the chief pathogen owing to its multiple virulence factors. C. albicans infections are usually treated with azoles, polyenes and echinocandins. However, these antifungals may have limitations regarding toxicity, relapse of infections, high cost, and emergence of antifungal resistance. Thus, the development of nanocarrier systems, such as metal nanoparticles, has been widely investigated. Metal nanoparticles are particulate dispersions or solid particles 10–100 nm in size, with unique physical and chemical properties that make them useful in biomedical applications. In this review, we focus on the activity of silver, gold, and iron nanoparticles against C. albicans. We discuss the use of metal nanoparticles as delivery vehicles for antifungal drugs or natural compounds to increase their biocompatibility and effectiveness. Promisingly, most of these nanoparticles exhibit potential antifungal activity through multi-target mechanisms in C. albicans cells and biofilms, which can minimize the emergence of antifungal resistance. The cytotoxicity of metal nanoparticles is a concern, and adjustments in synthesis approaches or coating techniques have been addressed to overcome these limitations, with great emphasis on green synthesis.

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“…The MIC of the tested compounds was determined using the bifold serial dilution method. These tested compounds could be attractive and alternative antibacterial compounds that open a new path in chemotherapy [46].…”

Section: Nanocomposites That Reveal Promising Antifungal Activitymentioning

confidence: 99%

Antibacterial, Antifungal and Antiviral Nanocomposites: Recent Advances and Mechanisms of Action

Warangkar¹,

Deshpande²,

Totewad³

et al. 2022

Biocomposites - Recent Advances [Working Title]

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Over the past ten years, there has been a significant increase in research into the study of nanocomposites. Nanocomposites vary in their physical and chemical properties. In today’s era, eco-friendly, nontoxic, biocompatible, biobased fillers and composites should be synthesized to increase their societal value in various aspects. These materials have seen extensive use across several industries, from biosensors to biomedicine. Great strides have been made in the field of Microbiology, particularly as Antibacterial agents, among these applications. The objective of this review is to present a thorough analysis of several Nanocomposites that reveal promising antibacterial activity. Such Nanocomposites are reviewed in detail, as well as their antibacterial efficacy is discussed.

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Attractive study of the antimicrobial, antiviral, and cytotoxic activity of novel synthesized silver chromite nanocomposites

Cited by 15 publications

References 58 publications

Fabrication, characterization, and antibacterial activity of ferrite, chromite, and aluminate nanoparticles

Fabrication, characterization, and antibacterial activity of ferrite, chromite, and aluminate nanoparticles

Metal Nanoparticles to Combat Candida albicans Infections: An Update

Antibacterial, Antifungal and Antiviral Nanocomposites: Recent Advances and Mechanisms of Action

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