Attitudes towards genetic testing: The role of genetic literacy, motivated cognition, and socio-demographic characteristics

Likhanov, Maxim; Zakharov, Ilya; Awofala, Adeyemi; Ogundele, Olusegun; Selita, Fatos; Kovas, Yulia; Chapman, Robert

doi:10.1371/journal.pone.0293187

Cited by 5 publications

(1 citation statement)

References 86 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In general, with the increasing focus on the empowerment of citizens and self-management in health and disease, a rising demand for information is to be expected in the future. The limited involvement in preventive genomics of both citizens and professionals, as well as limited genetic literacy, both pose challenges to such empowerment [77][78][79].…”

Section: Demandmentioning

confidence: 99%

Genetic Screening—Emerging Issues

Cornel,

van der Meij,

van El

et al. 2024

Genes

View full text Add to dashboard Cite

In many countries, some form of genetic screening is offered to all or part of the population, either in the form of well-organized screening programs or in a less formalized way. Screening can be offered at different phases of life, such as preconception, prenatal, neonatal and later in life. Screening should only be offered if the advantages outweigh the disadvantages. Technical innovations in testing and treatment are driving changes in the field of prenatal and neonatal screening, where many jurisdictions have organized population-based screening programs. As a result, a greater number and wider range of conditions are being added to the programs, which can benefit couples’ reproductive autonomy (preconception and prenatal screening) and improve early diagnosis to prevent irreversible health damage in children (neonatal screening) and in adults (cancer and cascade screening). While many developments in screening are technology-driven, citizens may also express a demand for innovation in screening, as was the case with non-invasive prenatal testing. Relatively new emerging issues for genetic screening, especially if testing is performed using DNA sequencing, relate to organization, data storage and interpretation, benefit–harm ratio and distributive justice, information provision and follow-up, all connected to acceptability in current healthcare systems.

show abstract

Section: Demandmentioning

confidence: 99%

Genetic Screening—Emerging Issues

Cornel,

van der Meij,

van El

et al. 2024

Genes

View full text Add to dashboard Cite

show abstract

Access to clinical genetic services: An evaluation of patient referral characteristics and identifying barriers in Michigan

Lemke,

Bupp,

Niemchick

2024

Journal of Genetic Counseling

View full text Add to dashboard Cite

The utilization of genetics in medical care has enhanced the utility of precision medicine and hence increased the need for clinical genetic services. These services have reduced the costs and expanded the availability of genetic testing, but their use is limited in certain populations. This study explores the access to clinical genetic services for Michigan patients referred to a genetics clinic on the western side of the state. Factors included the travel distance (miles), wait time for appointment (days from the referral date to the date of first appointment), population demographics, and cultural characteristics. A retrospective record review of all aged patients (n = 568) referred to a genetics clinic in 2018 demonstrated that all patients were insured (100%), of which majority were white‐non‐Hispanic (90.7%), more than half were < 10 years of age at referral (53.3%), and most of them kept their first appointment (93.5%). Our analysis showed that the wait time was associated with referral non‐compliance, p < 0.01. Adjusting for all variables, for each additional day in wait time, patients had 1% increased risk of not seeking clinical genetic services (OR = 1.01, 90% CI [1.01, 1.02]). Policies to encourage genetic service utilization and improve equitable access to precision health are needed. An opportunity exists for strategies that broaden and add diverse populations to those receiving genetic services.

show abstract