Attitudes to Mesalamine Questionnaire: A Novel Tool to Predict Mesalamine Nonadherence in Patients with IBD

Moss, Alan C.; Lillis, Yvonne; George, Jessica B. Edwards; Choudhry, Niteesh K.; Berg, Anders H.; Cheifetz, Adam S.; Horowitz, Gary L.; Leffler, Daniel A.

doi:10.1038/ajg.2014.158

Cited by 21 publications

(10 citation statements)

References 33 publications

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“…In practical studies, barriers to medication adherence are usually presented as a series of single factors without a definite classification (Moss et al, 2014;Müller et al, 2015;Newman-Casey et al, 2015;Xavier et al, 2016). The common barriers to medication adherence for CVD include unaffordable costs, lack of belief in the necessity of medication, side effects of medication or medication concerns, complex regimens, forgetfulness, lack of family or social support, depression, lack of disease knowledge, and inconvenient access to medications or care (Choudhry et al, 2011;Nair et al, 2011;Müller et al, 2015;Zullig et al, 2015;Banerjee et al, 2016;Crawshaw et al, 2016;Xavier et al, 2016;Wang et al, 2019).…”

Section: Detecting Barriers To Medication Adherencementioning

confidence: 99%

Tailored Interventions to Improve Medication Adherence for Cardiovascular Diseases

Zhang

et al. 2020

Front. Pharmacol.

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Over the past half-century, medical research on cardiovascular disease (CVD) has achieved a great deal; however, medication adherence is unsatisfactory. Nearly 50% of patients do not follow prescriptions when taking medications, which limits the ability to maximize their therapeutic effects and results in adverse clinical outcomes and high healthcare costs. Furthermore, the effects of medication adherence interventions are disappointing, and tailored interventions have been proposed as an appropriate way to improve medication adherence. To rethink and reconstruct methods of improving medication adherence for CVD, the literature on tailored interventions for medication adherence focusing on CVD within the last 5 years is retrieved and reviewed. Focusing on identifying nonadherent patients, detecting barriers to medication adherence, delivering clinical interventions, and constructing theories, this article reviews the present state of tailored interventions for medication adherence in CVD and also rethinks the present difficulties and suggests avenues for future development.

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Section: Detecting Barriers To Medication Adherencementioning

confidence: 99%

Tailored Interventions to Improve Medication Adherence for Cardiovascular Diseases

Zhang

et al. 2020

Front. Pharmacol.

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“…In addition, recognizing that poor adherence to mesalamine is common, Moss et al 45 developed a 10-item survey to assesses UC patient-reported barriers to mesalamine adherence and predict those at risk for future non-adherence. They found that patients' beliefs about the need for maintenance mesalamine and their concerns about side effects influenced their adherence to mesalamine over time.…”

Section: Factors Associated With Non-adherencementioning

confidence: 99%

Medication adherence in inflammatory bowel disease

et al. 2017

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Inflammatory bowel disease (IBD) is a chronic idiopathic inflammatory condition with intestinal and extraintestinal manifestations. Medications are the cornerstone of treatment of IBD. However, patients often adhere to medication poorly. Adherence to medications is defined as the process by which patients take their medications as prescribed. Treatment non-adherence is a common problem among chronic diseases, averaging 50% in developed countries and is even poorer in developing countries. In this review, we will examine the adherence data in IBD which vary greatly depending on the study population, route of administration, and methods of adherence measurement used. We will also discuss the adverse clinical outcomes related to non-adherence to medical treatment including increased disease activity, flares, loss of response to anti-tumor necrosis factor therapy, and so forth. There are many methods to measure medication adherence namely direct and indirect methods, each with their advantages and drawbacks. Finally, we will explore different intervention strategies to improve adherence to medications.

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“…3,4 Unfortunately, adherence to mesalamine regimens in general is poor, particularly when patients are in remission. 5,6 Nonadherence to mesalamine has negative implications for patients and the health care system; relapse rates, colorectal cancer prevalence, and health care costs are all greater in nonadherent patients than adherent ones. [7][8][9][10] Many patients report that their nonadherence with oral mesalamine is unintentional, e.g., they forget to take the pills.…”

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confidence: 99%

Adherence to Rectal Mesalamine in Patients with Ulcerative Colitis

Boyle

Ting

Cury

et al. 2015

Inflammatory Bowel Diseases

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Attitudes to Mesalamine Questionnaire: A Novel Tool to Predict Mesalamine Nonadherence in Patients with IBD

Abstract: Patients' beliefs about the need for maintenance mesalamine and their concerns about side effects influence their adherence to mesalamine over time. These concerns could easily be raised in practice to identify patients at risk of nonadherence (Clinical Trial number NCT01349504).

Cited by 21 publications

References 33 publications

Tailored Interventions to Improve Medication Adherence for Cardiovascular Diseases

Tailored Interventions to Improve Medication Adherence for Cardiovascular Diseases

Medication adherence in inflammatory bowel disease

Adherence to Rectal Mesalamine in Patients with Ulcerative Colitis

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