Attitudes regarding organ donation from non–heart-beating donors

Keenan, Sean; Hoffmaster, Barry; Rutledge, Frank; Eberhard, Jeannette; Chen, Liddy M.; Sibbald, William J.

doi:10.1053/jcrc.2002.33036

Cited by 34 publications

(29 citation statements)

References 38 publications

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“…Participants in the qualitative studies by Wolf (34), Curley et al (16), and D'Alessandro et al (19) also wished for consistently applied standardized protocols. The study by Keenan et al of the general public and HCPs supports this, with a vast majority of participants (90% health care workers and 94% general public) wanting formal hospital policies for decisions on medical futility (25).…”

Section: Call For Standardized Protocolsmentioning

confidence: 88%

Systematic Review of Attitudes Toward Donation After Cardiac Death Among Healthcare Providers and the General Public*

Bastami

Matthes

Krones

et al. 2013

Critical Care Medicine

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Identified themes were the levels of support for DBD vs. DCD, attitudes toward postmortem measures without previous consent, lack of knowledge about DCD, concerns about the Dead Donor Rule, the potential for conflict of interest, making donation happen, and the call for standardized DCD protocols. All of these issues are of ethical relevance and merit further discussion. We conclude that deep-rooted concerns about DCD exist among medical personnel and the general public. These need to be taken seriously in order to maintain or foster trust in the transplantation system.

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Section: Call For Standardized Protocolsmentioning

confidence: 88%

Systematic Review of Attitudes Toward Donation After Cardiac Death Among Healthcare Providers and the General Public*

Bastami

Matthes

Krones

et al. 2013

Critical Care Medicine

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“…While several centers in Holland and Great Britain routinely explant kidneys of non-heart-beating donors (1,17,13,30), this concept is not generally accepted within Europe. In fact it raises new questions concerning the criteria for determining when resuscitation should be stopped.…”

Section: Discussionmentioning

confidence: 99%

Renal Transplantation

Müller¹,

Petritsch²,

Wirnsberger³

et al. 2003

Eur Surg

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Background: Clinical renal transplantation has been performed successfully since 1955. With the introduction of Cyclosporin A to the market, 1982, results markedly improved, and allogeneic renal transplantation became a standard therapy in the treatment of end stage kidney failure. Life expectancy and quality of life is superior in kidney recipients in comparison with patients on dialysis. Methods: In our center 699, renal transplantations have been performed since 1968. 98.1 % of the transplanted kidneys were from cadaveric donors, 1.9 % from living related donors. Mean age of the recipients was 30.7 + 13.9 years from 1968 to 1983, and is now 45.9 + 13.1 (1999 to 2002). The kidneys are normally transplanted to the common iliac vessels in end-to-side fashion. A Politano-Leadbetter antirefluxive implantation of the ureter is obligatory. Results: 5-year graft survival was 19.4 % from 1968 to 1983, 74.3 % from 1984 to 1995, and 81.2 % from 1995 to 1998. Typical surgical complications are hematoma, lymphocele, ureter stenosis and ureter necrosis. The rate of necessary reoperations is 3.9 %. 5-year patient survival is 90 %. Heart disease (50 %), cancer (16 %), and sepsis (15 %) are the most frequent causes of death after renal transplantation. Conclusions: Renal transplantation continues to be the optimal treatment of terminal kidney failure. New immunosuppressive agents have improved the outcome after kidney transplantation. Enlargement of the donor pool is being attempted by the acceptance of older organs and by the acceptance of pediatric organs for adult recipients, too. (Eur. Surg. 2003; 35:315-320)Nierentransplantation Zusammenfassung: Grundlagen: Die Ära erfolgreicher klinischer Nierentransplantationen begann bereits 1955. Ab 1982, mit der Einführung von Cyclosporin A in die Immunsuppression, wurden gute Langzeitergebnisse erzielt, und Nierentransplantationen wurden zu einer Standardtherapie bei chronischem Nierenversagen. Lebensqualität und Lebenserwartung nierentransplantierter Patienten sind besser als bei vergleichbaren Patienten an der Dialyse. Methodik: Seit 1968 wurden an unserem Zentrum 699 Nierentransplantationen durchgeführt. 98,1 % der transplantierten Nieren stammten von hirntoten Organspendern und 1,9 % von verwandten Lebendspendern. Das mittlere Alter der Empfän-ger betrug in den Jahren 1968 bis 1983 30,7 + 13,9 Jahre und liegt nun bei 45,9 + 13,1 Jahren. End-Seit-Anastomosen an die Arteria und Vena iliaca communis, sowie eine antirefluxive Ureterimplantation nach Politano-Leadbetter sind Standard. Ergebnisse: Die 5-Jahres Überlebensrate der Transplantate lag von 1968 bis 1983 bei 19,4 %, von 1984 bis 1995 bei 74,3 % und von 1995 bis 1998 bei 81,2 %. Die Rate operativer Revisionen beträgt 3,9 %. Die häufigsten chirurgischen Komplikationen sind Hämatome, Lymphocelen, Ureterstenosen und Ureternekrosen. Das 5-Jahres Patientenüberleben liegt bei 90 %. Herzerkrankungen (50 %), Malignome (16 %) und Sepsis (15 %) sind die häufigsten Todesursachen nach Nierentransplantation. Schlussfolgerungen: Die Nieren...

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“…There is a danger that a would-be provider might have her organs removed while she is still alive by her own definition of death, though dead by the prevailing medical definition. Would-be providers may also fear the conflict of interest created for doctors that are responsible for the well-being of both the provider and recipient of the organs (Keenan et al, 2002;Shaw, 1993). Even if this risk of premature death is overblown in the conception of the general population, a smaller risk remains given differing conceptions of death.…”

Section: Are Cadaver Transfers "Easy"?mentioning

confidence: 99%

Easy Rescues and Organ Transplantation

Snyder

2009

HEC Forum

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Attitudes regarding organ donation from non–heart-beating donors

Cited by 34 publications

References 38 publications

Systematic Review of Attitudes Toward Donation After Cardiac Death Among Healthcare Providers and the General Public*

Systematic Review of Attitudes Toward Donation After Cardiac Death Among Healthcare Providers and the General Public*

Renal Transplantation

Easy Rescues and Organ Transplantation

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