Attenuation of hypertensive response with esmolol and labetalol in low doses in orotrachealintubation A comparative study

Abstract

Background:The golden standard is rigid laryngoscopy and tracheal intubation in airway management. Aim: To study efficacy in stress response prevention on laryngoscopy and intubation and to study hemodynamic parameters intraoperatively. Materials and Methods: This study was a prospective, randomised, double blinded study which was conducted .Results: In both the study groups had similar demographicpro file. During laryngoscopy and intubation, esmolol and labetalol showed rise in heart rate, systolic blood pressure and RPP, whereas the values for MAP and DBP was not statistically significant difference. Conclusion: Labetalol is more effective when compared to esmolol in attenuating the sympathomimetic effect of laryngoscopy and intubation in lower doses.