Attentional dysfunctions in neuroleptic-naive and neuroleptic-withdrawn schizophrenic patients and their siblings

Abnormal speech perception in schizophrenia with auditory hallucinations

“…Patients who took medication increased their ability through experience, so the rate of incorrect answers from CPT reduced (19, 20). There is some controversy regarding CPT performance, as it has been reported to be linked to the degree of severity of symptoms by some groups (22, 23), while others have disagreed (24). In our study, even though not statistically significant, there were some trends of improvement of cognitive measures after treatment.…”

Stimulating the Development of Drug Treatments to Improve Cognition in Schizophrenia

“…The magnitude of the cognitive impairment is relatively stable across clinical state. On some cognitive measures, the level of impairment shown by patients during a psychotic episode is remarkably similar to that seen when their symptoms are under control or when they are in full remission (Finkelstein et al 1997, Nuechterlein et al 1998. Therefore, cognitive impairment can occur with low levels, or complete absence, of clinical symptoms of schizophrenia.…”

Association of DISC1/TRAX Haplotypes With Schizophrenia, Reduced Prefrontal Gray Matter, and Impaired Short- and Long-term Memory

“…who was blind to zygosity and to the diagnostic status of the other co-twin. Variables selected for quantitative trait locus analysis consisted of 8 test indexes that discriminated affected from unaffected co-twins, degree of genetic loading for schizophrenia, or both, as previously described 27 : spatial working memory, 43 divided attention, 44 choice reaction time, 45 verbal learning and memory, 46 intrusions during verbal memory retrieval, 46 semantic clustering during verbal memory retrieval, 46 visuospatial learning and memory, 43 and motor speed. 47 All groups were within 1 SD of normal in terms of a composite average of the age-scaled standard scores on the vocabulary, similarities, block design, and digit symbol subtests of the Wechsler Adult Intelligence Test-Revised.…”