Attempts to Mimic Docking Processes of the Immune System: Recognition-Induced Formation of Protein Multilayers

Müller, W; Ringsdorf, Helmut; Rump, Elmar; Wildburg, Gerald; Zhang, X.; Angermaier, L.; Knoll, Wolfgang; Liley, Martha; Spinke, J.

doi:10.1126/science.8259513

Cited by 204 publications

(146 citation statements)

References 17 publications

Supporting

Mentioning

141

Contrasting

Unclassified

Order By: Relevance

“…The strong interaction between biotin and streptavidin groups has been used for LbL multilayer assemblies in 1993. 141,142 Interactions between biotin and avidin, 143 sugar and lectin, 144,145 or antigen and antibody 146 have also successfully lead to preparation of LbL films. The wide range of noncovalent interactions useful for performing the LbL process has resulted in an incredibly wide variety of systems.…”

Section: History Of Layer-by-layermentioning

confidence: 99%

Layer-by-layer Nanoarchitectonics: Invention, Innovation, and Evolution

et al. 2013

View full text Add to dashboard Cite

Materials fabrication with nanoscale structural precision based on bottom-up-type self-assembly has become more important in various current disciplines in chemistry including materials chemistry, organic chemistry, physical chemistry, analytical chemistry, biochemistry, colloid and surface chemistry, and supramolecular chemistry. Although the design of new materials based on nanoscale self-assembly is anticipated as a key concept, preparing complete three-dimensional structures at nanoscale precision remains a difficult target using current technologies. Rather, dimension-reduced approaches such as layering of two-dimensional nanostructures into precisely controlled lamellar nanomaterials are currently achievable. In particular, layer-by-layer (LbL) assembly is known as a highly versatile method for fabrication of controlled layered structures from various kinds of component materials using very simple, inexpensive, and rapid procedures. Therefore, fabrication of multilayer films through the LbL deposition process has attracted growing interest from various research communities. The high versatility and flexibility of LbL assembly is continuously creating new concepts, new materials, new procedures, and new applications. In this highlight review, we focus on nanoarchitectonics by LbL assembly. After an initial introduction on the invention and a brief history of the LbL assembly technique, innovations and the evolution of the technique are described based mainly on recent examples, which are categorized into two sections: (i) developments in methodology (technical, material, and phenomenological aspects with expansion of concept) and (ii) progress in applications (physical, chemical/biochemical, and biomedical applications).

show abstract

Section: History Of Layer-by-layermentioning

confidence: 99%

Layer-by-layer Nanoarchitectonics: Invention, Innovation, and Evolution

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Some types of self-assembly and self-organization are achieved by covalent bonding of sulfur-bearing compounds on zero-valent metals such as gold, silver, platinum, and copper [1][2][3][4][5]. The controlled construction of ordered supermolecular organic structures on metal surfaces will help our understanding of twodimensional systems, such as biomembranes that play important roles in molecular recognition, signal transduction, and signal processing which are essential for cellular functions.…”

mentioning

confidence: 99%

Single Molecule Imaging of Fluorescently Labeled Proteins on Metal by Surface Plasmons in Aqueous Solution

Yokota

Saito²,

Yanagida

1998

Phys. Rev. Lett.

View full text Add to dashboard Cite

We report the first real time imaging of single fluorophores attached to protein molecules on metal surfaces in aqueous solution using surface plasmon resonance fluorescence microscopy. The fluorescence was enhanced by the surface plasmons as theoretically predicted for gold and silver. Active movement of single molecules of the fluorescently labeled motor protein, coupled to the ATPase reaction, was observed on the surfaces of gold and aluminum. This microscopy should prove a powerful tool to directly detect single molecule processes in biomolecule systems organized on a metal surface.[ S0031-9007(98)

show abstract

“…Highly stable molecular layers prepared by the step-bystep self-assembly method were used for developing hybrid devices [46,47] as illustrated schematically in figure 1(a). First, the commercially available microcantilever was cleaned using piranha solution (a mixture of 3:7 v/v of 30% H 2 O 2 and 98% H 2 SO 4 ) for 25 min, and rinsed with double distilled water three times for 5 min, followed by drying under clean air.…”

Section: Assembling Purple Membrane On the Gold Surface Of Microcantimentioning

confidence: 99%

A nanomechanical device based on light-driven proton pumps

Ren¹,

Zhao²,

Han³

et al. 2006

Nanotechnology

View full text Add to dashboard Cite

In this paper, a hybrid device based on a microcantilever interfaced with bacteriorhodopsin (bR) is constructed. The microcantilever, on which the highly oriented bR film is self-assembled, undergoes controllable and reversible bending when the light-driven proton pump protein, bR, on the microcantilever surface is activated by visible light. Several control experiments are carried out to preclude the influence of heat and photothermal effects. It is shown that the nanomechanical motion is induced by the resulting gradient of protons, which are transported from the KCl solution on the cytoplasmic side of the bR film towards the extracellular side of the bR film. Along with a simple physical interpretation, the microfabricated cantilever interfaced with the organized molecular film of bR can simulate the natural machinery in converting solar energy to mechanical energy.

show abstract

Attempts to Mimic Docking Processes of the Immune System: Recognition-Induced Formation of Protein Multilayers

Cited by 204 publications

References 17 publications

Layer-by-layer Nanoarchitectonics: Invention, Innovation, and Evolution

Layer-by-layer Nanoarchitectonics: Invention, Innovation, and Evolution

Single Molecule Imaging of Fluorescently Labeled Proteins on Metal by Surface Plasmons in Aqueous Solution

A nanomechanical device based on light-driven proton pumps

Contact Info

Product

Resources

About