Attempt to fulfil Koch's postulates for pyloric Campylobacter

Marshall, Barry J.; Ja, Armstrong; Db, McGechie; Rj, Glancy

doi:10.5694/j.1326-5377.1985.tb113443.x

Cited by 1,124 publications

(384 citation statements)

References 11 publications

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“…A recent study found H pylori in 10% of tracheal aspirates from patients with aspiration pneumonia 46. The incubation period for H pylori from inoculation to symptoms is three to seven days,47 48 followed by 7–49 days of achlorhydria49 with a possible enhanced infection risk from other organisms. Therefore, delayed handling by siblings combined with this incubation period and waning maternal antibodies may account for the absence of SIDS in the first month of life.…”

Section: Discussionmentioning

confidence: 99%

An association between sudden infant death syndrome (SIDS) and Helicobacter pylori infection

Kerr

Al-Khattaf

Barson

et al. 2000

Archives of Disease in Childhood

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Background-Helicobacter pylori has recently been detected in the stomach and trachea of cases of sudden infant death syndrome (SIDS) and proposed as a cause of SIDS. Aims-To establish the incidence of H pylori in the stomach, trachea, and lung of cases of SIDS and controls. Methods-Stomach, trachea, and lung tissues from 32 cases of SIDS and eight control cases were examined retrospectively. Diagnosis of SIDS was based on established criteria. Controls were defined by death within 1 year of age and an identifiable cause of death. Tissues were examined histologically for the presence of bacteria. Extracted DNA from these tissues was tested for H pylori ureC and cagA sequences by nested polymerase chain reaction and amplicons detected by enzyme linked immunosorbent assay (ELISA). The cut oV for each ELISA for each of the tissue types was taken as the mean optical density plus two times the standard deviation of a range of negative controls. Results-Ages of SIDS cases ranged from 2 to 28 weeks. Ages of controls ranged from 3 to 44 weeks. For the ureC gene, 25 SIDS cases were positive in one or more tissues compared with one of the controls. For the cagA gene, 25 SIDS cases were positive in one or more tissues compared with one of the controls. Conclusions-There is a highly significant association between H pylori ureC and cagA genes in the stomach, trachea, and lung of cases of SIDS when compared with controls.

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Section: Discussionmentioning

confidence: 99%

An association between sudden infant death syndrome (SIDS) and Helicobacter pylori infection

Kerr

Al-Khattaf

Barson

et al. 2000

Archives of Disease in Childhood

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show abstract

“…Acute iatrogenic or self-administered infection with H. pylori can induce acute dyspeptic symptoms 32 33. However, while persistent colonisation virtually always leads to chronic gastritis, in the majority of subjects the symptoms are transient.…”

Section: Working Group 1: Indications/associationsmentioning

confidence: 99%

Management ofHelicobacter pyloriinfection—the Maastricht V/Florence Consensus Report

Malfertheiner

Mégraud

O’Moráin

et al. 2016

Gut

2,444

3,052

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“…There are two studies which need to be considered. In the first one by Marshall et al inoculation resulted in dyspepsia on day 7 and biopsy proved gastritis in the presence of H pylori at day 10 6. Gastric biopsies on day 14 showed a decrease in gastritis, and organisms could no longer be recovered.…”

Section: Does Helicobacter Pylori Cause Peptic Ulcers?mentioning

confidence: 99%

Controversies in Management: Helicobacter pylori is not the causative agent

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1994

BMJ

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Attempt to fulfil Koch's postulates for pyloric Campylobacter

Cited by 1,124 publications

References 11 publications

An association between sudden infant death syndrome (SIDS) and Helicobacter pylori infection

An association between sudden infant death syndrome (SIDS) and Helicobacter pylori infection

Management ofHelicobacter pyloriinfection—the Maastricht V/Florence Consensus Report

Controversies in Management: Helicobacter pylori is not the causative agent

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