“…[4][5][6] It could also be hypothesized that malnutrition could cause neurodegeneration or microvascular lesions. Although evidence supporting this hypothesis is scarce, previous studies in individuals with anorexia nervosa and individuals undergoing dialysis have shown that severe weight loss is related to greater risk of brain atrophy 7 and that lower body fat is related to white matter hyperintensities (WMHs). 8 It has been found that malnutrition at the micronutrient level may aggravate brain pathology in old age.…”
Malnutrition and lower vitamin B1 and B12 levels were independently associated with greater risk of WMHs. Underlying mechanisms need to be further clarified, and whether nutritional interventions can modify these findings also needs to be studied.
“…[4][5][6] It could also be hypothesized that malnutrition could cause neurodegeneration or microvascular lesions. Although evidence supporting this hypothesis is scarce, previous studies in individuals with anorexia nervosa and individuals undergoing dialysis have shown that severe weight loss is related to greater risk of brain atrophy 7 and that lower body fat is related to white matter hyperintensities (WMHs). 8 It has been found that malnutrition at the micronutrient level may aggravate brain pathology in old age.…”
Malnutrition and lower vitamin B1 and B12 levels were independently associated with greater risk of WMHs. Underlying mechanisms need to be further clarified, and whether nutritional interventions can modify these findings also needs to be studied.
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