Atrioventricular Septal Defects

Chaudhry, Anisa; Urbinelli, Lindsay; Veldtman, Gruschen

doi:10.1016/b978-0-7020-6929-1.00031-9

Cited by 4 publications

(7 citation statements)

References 41 publications

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“…Complete AVSD was the most common form in both groups. Conversely, partial AVSD was identified only in the group WDS in our cohort, while transitional AVSD were distributed similarly in both groups as showed by other reports ( 2 , 3 ). Almost 13% of AVSD had unbalanced ventricles, compared to a prevalence of 10% in literature ( 22 , 23 ).…”

Section: Discussionsupporting

confidence: 88%

“…The prevalence of complete AVSD was almost 80%, slightly more than in other published reports ( 2 , 3 ). Complete AVSD was the most common form in both groups.…”

Section: Discussionmentioning

confidence: 49%

“…Intermediate or transitional AVSDs consists of an ostium primum defect in association with a restrictive inlet ventricular defect and two valvular orifices. Unbalanced AVSD is defined as malalignment of the atrioventricular valve, being unequal for both ventricles, resulting in one ventricle receiving more blood flow and the other ventricle being underdeveloped (hypoplastic) ( 2 ).…”

Section: Methodsmentioning

confidence: 99%

“…The cardiac diagnoses were presented in accordance to the classification of the International Pediatric and Congenital Cardiac Code ( 2 ). The statistical analysis is descriptive.…”

Section: Methodsmentioning

confidence: 99%

“…AVSD accounts for 4–5% of total congenital heart diseases ( 1 ). The International Pediatric and Congenital Cardiac Code classified AVSDs into four main groups: complete, partial (or incomplete), intermediate (or transitional), and AVSDs with ventricular imbalance (unbalanced AVSD) ( 2 ). Most AVSDs are complete (up to 75%), and account for 3% of all cardiac malformations ( 2 , 3 ).…”

Section: Introductionmentioning

confidence: 99%

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Challenges in the Surgical Treatment of Atrioventricular Septal Defect in Children With and Without Down Syndrome in Romania-A Developing Country

et al. 2021

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Background: Atrioventricular septal defect (AVSD) is a cardiac malformation that accounts for up to 5% of total congenital heart disease, occurring with high frequency in people with Down Syndrome (DS). We aimed to establish the surgical challenges and outcome of medical care in different types of AVSD in children with DS compared to those without DS (WDS).Methods: The study included 62 children (31 with DS) with AVSD, evaluated over a 5 year period.Results: Complete AVSD was observed in 49 (79%) children (27 with DS). Six children had partial AVSD (all WDS) and seven had intermediate types of AVSD (4 with DS). Eight children had unbalanced complete AVSD (1 DS). Median age at diagnosis and age at surgical intervention in complete AVSD was not significantly different in children with DS compared to those WDS (7.5 months vs. 8.6). Median age at surgical intervention for partial and transitional AVSDs was 10.5 months for DS and 17.8 months in those without DS. A large number of patients were not operated: 13/31 with DS and 8/31 WDS.Conclusion: The complete form of AVSD was more frequent in DS group, having worse prognosis, while unbalanced AVSD was observed predominantly in the group without DS. Children with DS required special attention due to increased risk of pulmonary hypertension. Late diagnosis was an important risk factor for poor prognosis, in the setting of suboptimal access to cardiac surgery for patients in Romania. Although post-surgery mortality was low, infant mortality before surgery remains high. Increased awareness is needed in order to provide early diagnosis of AVSD and enable optimal surgical treatment.

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Section: Discussionsupporting

confidence: 88%

“…The prevalence of complete AVSD was almost 80%, slightly more than in other published reports ( 2 , 3 ). Complete AVSD was the most common form in both groups.…”

Section: Discussionmentioning

confidence: 49%

Section: Methodsmentioning

confidence: 99%

“…The cardiac diagnoses were presented in accordance to the classification of the International Pediatric and Congenital Cardiac Code ( 2 ). The statistical analysis is descriptive.…”

Section: Methodsmentioning

confidence: 99%