Atrial natriuretic peptide responses during anaesthesia in patients with refractory cardiomyopathies

Abstract

In patients with congestive heart failure, the release of atrial natriuretic peptide (ANP)

Adverse Cardiovascular Effects of Ketamine Infusion in Patients with Catecholamine-Dependent Heart Failure

“…Similar unfavourable haemodynamic effects of ketamine have been reported in previous studies during induction of anaesthesia in patients with cardiomyopathy undergoing heart transplantation 8,9 . However, in these studies any adverse longterm haemodynamic effects of ketamine were without consequence, since the diseased heart was removed soon after drug application.…”

“…Nevertheless, both studies revealed also a significant adverse effect related to an undesirable ketamineinduced increase in pulmonary artery pressure. This potential negative effect of ketamine infusion has also been demonstrated in other studies with cardiac patients [8][9][10] . As pulmonary vascular resistance is often already elevated in septic patients and patients with pulmonary or cardiac disease, further increases of right ventricular afterload by ketamine might be of clinical relevance.…”

Endocrine Response After Severe Subarachnoid Hemorrhage Related to Sodium and Blood Volume Regulation

“…However, a lack of relation between sedation and sodium excretion has been reported in the literature 44 and most of our patients were constantly sedated during periods 1 and 2 when the most consistent changes were observed.…”