Atrial myxoma in a family

Siltanen, P; Tuuteri, L; Norio, Reijo; Tala, P; Ahrenberg, P.; Halonen, Pentti I.

doi:10.1016/0002-9149(76)90158-2

Cited by 44 publications

(9 citation statements)

References 22 publications

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“…2 Two recent series utilizing the biatrial approach, exclusively, reported minimal morbidity. 21,25 Although its neoplastic nature has been questioned, 22 aneuploidy and familial occurrence of myxomas 23,[26][27][28][29][30] offer strong support of neoplastic nature. Although immunohistochemical studies support a multipotential mesenchymal cell as the cell of origin of myxomas, 16,[31][32][33][34] recent data may suggest another embryologic origin.…”

Section: Discussionmentioning

confidence: 99%

Atrial Myxomas: Pathologic Types, Tumor Location, and Presenting Symptoms

et al. 2006

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Section: Discussionmentioning

confidence: 99%

Atrial Myxomas: Pathologic Types, Tumor Location, and Presenting Symptoms

et al. 2006

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“…Up to 75% of cases (Buckley and Hutchins, 1979) occur in females, and the majority are diagnosed in the fifth or sixth decades of life. A family in which one parent and three out of seven siblings had atrial myxomas has also been described (Siltanen et al, 1976).…”

Section: Discussionmentioning

confidence: 99%

Bi-atrial myxomas presenting as recurrent pulmonary emboli in a girl

Hanly

Buitleir

Shaw

et al. 1984

Postgraduate Medical Journal

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SummaryA 14-year-old girl whose sole presenting features were symptoms of pulmonary embolism, was found to have bi-atrial myxomas. The diagnosis was made preoperatively, and the patient had a successful outcome following elective surgery. The absence of other features such as systemic embolism, atrioventricular valvular obstruction, fever and constitutional symptoms makes this a most unusual case. Right atrial myxoma should be considered in any patient presenting with pulmonary embolism for which there is no obvious source.

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“…Multifocal disease is frequent in the familial setting 4 . Recurrence has been associated with abnormal DNA ploidy in up to 40% of the patients.…”

Section: Commentmentioning

confidence: 99%

Cardiac Myxoma with Three Recurrences

Vohra

Patel

2002

J R Soc Med

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3. Myalgia and myoclonus are frequently noted. RDX is metabolized in the liver to carbon dioxide, bicarbonate and formic acid and excretion is via the kidneys. The elimination half-life is 15 hours. The toxic dose of RDX is unknown but there is a case report of a 3-year-old who ingested 84.82 mg/kg and survived 4. In rats the lethal dose is about 200 mg/kg when it is given as a 4% solution 5. Treatment is symptomatic and supportive, the most important points being control of seizures and maintenance of oxygenation. Polyisobutylene is a hydrocarbon and the principal acute hazard is aspiration, leading to pneumonitis and chronic lung dysfunction. Other acute effects of inhalation include cardiac arrhythmias and central nervous system depression. Nausea and vomiting may follow ingestion, and acute tubular necrosis, proteinuria and haematuria may develop. As with RDX, management is supportive, with particular attention to the respiratory system. Patients with a normal chest X-ray and no symptoms 6 hours after ingestion can be discharged. Amongst ®eld troops in Vietnam it became common knowledge that ingestion of a small amount of C-4 would produce a`high' similar to that of ethanol, and it is possible that this was the reason for this episode 2. The patient's clinical picture was dominated by the effects of RDX, with few from polyisobutylene. The help provided by the Poisons Information Services was invaluable.

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Atrial myxoma in a family

Cited by 44 publications

References 22 publications

Atrial Myxomas: Pathologic Types, Tumor Location, and Presenting Symptoms

Atrial Myxomas: Pathologic Types, Tumor Location, and Presenting Symptoms

Bi-atrial myxomas presenting as recurrent pulmonary emboli in a girl

Cardiac Myxoma with Three Recurrences

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